Genes Regulated by HPV 16 E6 and High Expression of NFX1-123 in Cervical Cancers.
Sreenivasulu ChintalaJustine LevanKristin RobinsonKevin QuistRachel A KatzenellenbogenPublished in: OncoTargets and therapy (2020)
In cervical cancer, NFX1-123 is highly expressed, and 16E6 and NFX1-123 together alter the expression of a wide set of genes. The involvement of these genes in cell proliferation, differentiation, invasion, and metastasis provides further insight into potential ways that HR HPVs promote cancer initiation and maintenance.