Combined Dexamethasone and Dexmedetomidine as Adjuncts to Popliteal and Saphenous Nerve Blocks in Patients Undergoing Surgery of the Foot or Ankle: A Randomized, Blinded, Placebo-controlled, Clinical Trial.
Mathias MaagaardKamilia S FunderNikolaj K SchouJeannette Ø PennyPeter ToquerJens LaigaardEmma R StormholtAnders K NørskovPia JægerJakob H AndersenOle MathiesenPublished in: Anesthesiology (2024)
Dexamethasone with or without dexmedetomidine increased the duration of analgesia in patients undergoing surgery of the foot or ankle with a popliteal (sciatic) and saphenous nerve block. Combined dexamethasone and dexmedetomidine did not increase the duration of analgesia when compared with dexamethasone.
Keyphrases
- coronary artery bypass
- patients undergoing
- high dose
- low dose
- minimally invasive
- clinical trial
- placebo controlled
- cardiac surgery
- double blind
- study protocol
- percutaneous coronary intervention
- pain management
- phase ii
- ultrasound guided
- peripheral nerve
- randomized controlled trial
- open label
- surgical site infection
- acute kidney injury
- phase iii
- spinal cord
- phase ii study
- atrial fibrillation
- rectal cancer