Efficacy and safety of avatrombopag in combination with immunosuppressive therapy in treatment-naïve and relapsed/refractory severe aplastic anaemia: protocol for the DIAAMOND-Ava-FIRST and DIAAMOND-Ava-NEXT Bayesian Optimal Phase II trials.

Zoe K McQuiltenStephane HeritierLucy FoxVanessa FoxLauren YoungPiers BlomberyIlona CunninghamJennifer CurnowAlisa HigginsDevendra K HiwaseRobin FilshieFrank FirkinPaul LacazeKylie MasonAnthony K MillsDominic PepperellSushrut PatilWilliam StevensonJeff SzerNeil WatersKate WilsonStephen TingErica Wood

Published in: BMJ open (2024)

ACTRN12619001042134, ACTRN12619001043123.

Keyphrases

phase ii
clinical trial
acute lymphoblastic leukemia
acute myeloid leukemia
randomized controlled trial
multiple myeloma
early onset
hodgkin lymphoma
double blind
phase iii
combination therapy
smoking cessation