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Endostatin 33 Peptide Is a Deintegrin α6β1 Agent That Exerts Antitumor Activity by Inhibiting the PI3K-Akt Signaling Pathway in Prostate Cancer.

Yang LiuChang-Lin WangZhong-Qi PangKe GaoLin-Kun ShenWan-Hai XuMing-Hua Ren
Published in: Journal of clinical medicine (2023)
The endostatin 33 peptide can exert antitumor effects by inhibiting the PI3K-Akt pathway, especially in tumors with a high expression of the integrin α6β1 subtype, such as prostate cancer. Therefore, our study will provide a new method and theoretical basis for the treatment of prostate cancer.
Keyphrases
  • prostate cancer
  • signaling pathway
  • radical prostatectomy
  • poor prognosis
  • pi k akt
  • recombinant human
  • cell proliferation
  • oxidative stress
  • long non coding rna
  • cell migration