Roux-en-Y Gastric Bypass Improved Insulin Resistance via Alteration of the Human Gut Microbiome and Alleviation of Endotoxemia.
Qiping ShiQian WangHui ZhongDehai LiShuxing YuHengwen YangCunchuan WangZhinan YinPublished in: BioMed research international (2021)
Our findings uncovered links between intestinal microbiota alterations, circulating endotoxemia, and insulin resistance. This suggests that the underlying mechanism of protection of the intestine by RYGB in obesity may be through changing the gut microbiota.
Keyphrases
- roux en y gastric bypass
- insulin resistance
- weight loss
- gastric bypass
- metabolic syndrome
- high fat diet induced
- adipose tissue
- high fat diet
- obese patients
- skeletal muscle
- polycystic ovary syndrome
- endothelial cells
- lps induced
- type diabetes
- bariatric surgery
- induced pluripotent stem cells
- glycemic control
- pluripotent stem cells
- weight gain
- inflammatory response
- physical activity