Impact of a non-fluoridated microcrystalline hydroxyapatite dentifrice on enamel caries progression in highly caries-susceptible orthodontic patients: A randomized, controlled 6-month trial.
Ulrich SchlagenhaufKarl-Heinz KunzelmannChristian HannigTheodor W MayHelmut HöslMario GratzaGabriele ViergutzMarco NazetSebastian SchambergerPeter ProffPublished in: Journal of investigative and clinical dentistry (2019)
In highly caries-active patients, the impact of the regular use of a microcrystalline HAP dentifrice on caries progression is not significantly different from the use of a 1400 ppm fluoride toothpaste (ClinicalTrials.gov: NCT02705456).