GATA6 Expression Distinguishes Classical and Basal-like Subtypes in Advanced Pancreatic Cancer.
Grainne M O'KaneBarbara T GrünwaldGun-Ho JangMehdi MasoomianSarah PicardoRobert C GrantRobert E DenrocheAmy ZhangYifan WangBernard LamPaul M KrzyzanowskiIllinca M LunguJohn M S BartlettMelanie PeraltaForam VyasSanjay SawJames BiagiDianne ChadwickStephanie RamotarShawn HutchinsonAnna DoddJulie M WilsonFaiyaz NottaGeorge ZogopoulosSteven GallingerJennifer J KnoxSandra E FischerPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2020)
The basal-like subtype is chemoresistant and can be distinguished from classical PDAC by GATA6 expression.See related commentary by Collisson, p. 4715.