Survival Outcomes of Calcium Channel Blocker Therapy in Patients With Non-Small Cell Lung Cancer Treated With Epidermal Growth Factor Receptor Inhibitors: A Retrospective Study.
Hui-Hsia HsiehTien-Yuan WuChi-Hua ChenYu-Hung KuoMann-Jen HourPublished in: Integrative cancer therapies (2023)
Calcium channels have been implicated in cancer pathogenesis. Our findings revealed the potential additive anticancer effects of CCBs when used concomitantly with EGFR-TKIs. However, study limitations, including the retrospective nature and small number of patients, necessitate large-scale prospective studies on the therapeutic potential of CCB as an adjunctive therapy with EGFR-TKIs in patients with NSCLC.
Keyphrases
- epidermal growth factor receptor
- advanced non small cell lung cancer
- tyrosine kinase
- small cell lung cancer
- newly diagnosed
- end stage renal disease
- ejection fraction
- peritoneal dialysis
- papillary thyroid
- single cell
- cross sectional
- mesenchymal stem cells
- squamous cell carcinoma
- stem cells
- climate change
- brain metastases
- patient reported
- childhood cancer
- replacement therapy