An Indirect Treatment Comparison of Semaglutide 2.0 mg vs Dulaglutide 3.0 mg and 4.5 mg Using Multilevel Network Meta-regression.

Ildiko LingvayRobert BauerJames Baker-KnightJack LawsonRichard E Pratley

Published in: The Journal of clinical endocrinology and metabolism (2022)

This ITC demonstrated significantly greater reductions from baseline in HbA1c and body weight with semaglutide 2.0 mg vs dulaglutide 3.0 mg and 4.5 mg. The findings of this study provide important comparative effectiveness information until randomized head-to-head studies become available.

Keyphrases

body weight
open label
double blind
randomized controlled trial
social media
placebo controlled
combination therapy
smoking cessation