The permissive role of TCTP in PM2.5/NNK-induced epithelial-mesenchymal transition in lung cells.
Li-Zhong LiuMenghuan WangQihang XinBowen WangGeorge G ChenMing-Yue LiPublished in: Journal of translational medicine (2020)
Our results provided new insights into the mechanisms of TCTP regulatory expression in lung carcinogens-induced EMT. TCTP and miR-125a-3p might act as potential prognostic biomarkers and therapeutic targets for NSCLC.
Keyphrases
- epithelial mesenchymal transition
- high glucose
- diabetic rats
- induced apoptosis
- small cell lung cancer
- poor prognosis
- signaling pathway
- air pollution
- drug induced
- heavy metals
- particulate matter
- cell cycle arrest
- risk assessment
- endothelial cells
- climate change
- transcription factor
- cell death
- long non coding rna
- pi k akt