Effect of storage time of platelet products on clinical outcomes after transfusion: a systematic review and meta-analyses.
Aukje L KreugerC Caram-DeelderJ JacobseJ-L KerkhoffsJ G van der BomRutger A MiddelburgPublished in: Vox sanguinis (2017)
Old platelets increase the risk of transfusion reactions in the setting of non-leucoreduction, shorten platelet transfusion intervals, thereby increase the numbers of platelet transfusions in haematological patients, and may increase the risk of bleeding.