Expression of oxidized protein tyrosine phosphatase and γH2AX predicts poor survival of gastric carcinoma patients.

Usama Khamis HusseinHo Sung ParkJun Sang BaeKyoung Min KimYun Jo ChongChan Young KimKeun Sang KwonMyoung Ja ChungHo LeeMyoung Jae KangWoo Sung MoonKyu Yun Jang

Published in: BMC cancer (2018)

This study suggests that oxidative stress-mediated oxidation of PTP might be involved in the progression of gastric carcinomas. In addition, this study suggests that individual and co-expression pattern of nuclear oxidized-PTP and γH2AX might be used as a prognostic marker of gastric carcinomas.

Keyphrases

poor prognosis
binding protein
ejection fraction
high grade
prognostic factors
nitric oxide
hydrogen peroxide
long non coding rna
endoplasmic reticulum stress