Human bronchial epithelial cells from patients with asthma have an altered gene expression profile.
Sangita BhakerMichael A PortelliKamini RakkarDominick E ShawSimon R JohnsonChristopher BrightlingIan SayersPublished in: ERJ open research (2022)
Gene changes observed in asthma bronchial epithelial cells are maintained following repeated culture, presenting with an exaggerated response to viral infection and immune responses as well as having differences in the rate of cell division and replication https://bit.ly/3Cq2xKf.
Keyphrases
- gene expression
- chronic obstructive pulmonary disease
- immune response
- lung function
- endothelial cells
- allergic rhinitis
- single cell
- dna methylation
- genome wide
- induced pluripotent stem cells
- copy number
- cell therapy
- case report
- pluripotent stem cells
- stem cells
- toll like receptor
- dendritic cells
- air pollution
- transcription factor