18F-FACBC PET/MRI in the evaluation of human brain metastases: a case report.
Knut JohannessenErik Magnus BerntsenHåkon JohansenTora S SolheimAnna KarlbergLive EikenesPublished in: European journal of hybrid imaging (2021)
Analysis showed high tumour-to-background ratios in brain metastases compared to other amino acid PET tracers, including high uptake in a very small cerebellar metastasis, suggesting that 18F-FACBC PET can provide early detection of otherwise overlooked metastases. Further studies to determine a threshold for 18F-FACBC brain tumour boundaries and explore its utility in clinical practice should be performed.
Keyphrases
- brain metastases
- small cell lung cancer
- pet ct
- positron emission tomography
- computed tomography
- clinical practice
- amino acid
- pet imaging
- endothelial cells
- contrast enhanced
- resting state
- white matter
- diffusion weighted imaging
- induced pluripotent stem cells
- pluripotent stem cells
- functional connectivity
- subarachnoid hemorrhage