Intensity-Modulated Radiotherapy is Superior to Three-Dimensional Conformal Radiotherapy in the Trimodality Management of Muscle-Invasive Bladder Cancer with Daily Cone Beam Computed Tomography Optimization.
Alexander D SherryAdam StewartGuozhen LuoAustin N KirschnerPublished in: Journal of radiation oncology (2019)
IMRT is superior to 3D-CRT for bladder cancer and spares dose to bowel, rectum, and bladder with improved acute toxicity compared to published clinical literature. For boost treatment, daily full bladder volume and positioning are not always reproducible, supporting the need for CBCT for optimal localization of the primary bladder tumor.
Keyphrases
- muscle invasive bladder cancer
- cone beam computed tomography
- spinal cord injury
- early stage
- locally advanced
- urinary tract
- physical activity
- radiation induced
- radiation therapy
- liver failure
- systematic review
- oxidative stress
- squamous cell carcinoma
- randomized controlled trial
- drug induced
- magnetic resonance imaging
- rectal cancer
- heart failure
- combination therapy
- contrast enhanced
- dual energy