Perfect adaptation of CD8+ T cell responses to constant antigen input over a wide range of affinities is overcome by costimulation.
Nicola TrendelPhilipp KrugerStephanie GaglioneJohn NguyenJohannes PettmannEduardo D SontagOmer DushekPublished in: Science signaling (2021)
Reduced T cell responses by contrast antigen stimulation can be rescued by signals from costimulatory receptors.
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