Paratrimerin Z, an undescribed chromene derivative from the roots of Paramignya trimera .

From an EtOAc-soluble fraction of the roots of Paramignya trimera , one undescribed chromene derivative, paratrimerin Z ( 1 ), was isolated. Its structure was elucidated on the basis of NMR spectroscopic interpretation. The absolute configuration of 1 was determined by the specific rotation analysis of its acid-catalyzed hydrolysis product. Paratrimerin Z ( 1 ), at a concentration of 100  μ M, did not show cytotoxicity against Hep3B human liver cancer cell line.