Apoptotic effects of human amniotic fluid mesenchymal stem cells conditioned medium on human MCF-7 breast cancer cell line.

Roghiyeh Pashaei-AslMaryam PashaiaslEsmaeil EbrahimieMaryam Lale AtaeiMaliheh Paknejad

Published in: BioImpacts : BI (2022)

Our finding demonstrated that hAFMSCs-CM presents apoptotic effect on MCF-7 cells; therefore, the application of hAFMSCs-CM, as a therapeutic reagent, can suppress breast cancer cells' viabilities and induce apoptosis.

Keyphrases

breast cancer cells
cell death
cell cycle arrest
endothelial cells
mesenchymal stem cells
induced apoptosis
induced pluripotent stem cells
oxidative stress
pluripotent stem cells
endoplasmic reticulum stress
cell proliferation
pi k akt
young adults