Altered ventricular longitudinal strain in children with sickle cell disease: Role of TGF-β and IL-18.

Reham WagdyHala AssemAli M Abd-ElmohsenAya FataWessam El GendyMarwa Gaber

Published in: Pediatric blood & cancer (2023)

The TGF-β, IL-18, and LDH along with frequent VOCs are correlated to altered LS, especially the right ventricle, and could serve as risk indicators for subclinical cardiomyopathy in children with SCD.

Keyphrases

young adults
heart failure
transforming growth factor
pulmonary hypertension
cross sectional
congenital heart disease