Phylogenomics revealed migration routes and adaptive radiation timing of Holarctic malaria mosquito species of the Maculipennis Group.
Andrey A YurchenkoAnastasia N NaumenkoGleb N ArtemovDmitry A KaragodinJames M HodgeAlena I VelichevskayaAlina A KokhanenkoSemen M BondarenkoMohammad R AbaiMaryam KamaliMikhail I GordeevAnton V MoskaevBeniamino CaputoSargis A AghayanElina M BarichevaVladimir N StegniyMaria V SharakhovaIgor V SharakhovPublished in: BMC biology (2023)
Our phylogenomic analyses reveal migration routes and adaptive radiation timing of Holarctic malaria vectors and strongly support the inclusion of An. beklemishevi into the Maculipennis Subgroup. Detailed knowledge of the evolutionary history of the Maculipennis Subgroup provides a framework for examining the genomic changes related to ecological adaptation and susceptibility to human pathogens. These genomic variations may inform researchers about similar changes in the future providing insights into the patterns of disease transmission in Eurasia.
Keyphrases
- plasmodium falciparum
- genome wide
- copy number
- endothelial cells
- single cell
- healthcare
- phase iii
- climate change
- radiation induced
- aedes aegypti
- gram negative
- current status
- induced pluripotent stem cells
- dna methylation
- clinical trial
- human health
- antimicrobial resistance
- dengue virus
- risk assessment
- randomized controlled trial
- zika virus
- gene therapy
- double blind
- drug induced