Comparative Inhibitory Effects of Tacrolimus, Cyclosporine, and Rapamycin on Human Anti-Pig Xenogeneic Mixed Lymphocyte Reactions.

Man ZhangHao FengJiaxiang DuSong ChenLan ZhuYi WangDengke Pan Gang Chen

Published in: Xenotransplantation (2024)

Tac is more efficient than CsA or Rapa in inhibiting xenogeneic T-cell responses in vitro. If used in combination with anti-CD154 mAb, all the three immunosuppressants can achieve satisfactory synergistic inhibitory effects.

Keyphrases

endothelial cells
signaling pathway
induced pluripotent stem cells
peripheral blood
cancer therapy
pluripotent stem cells
drug delivery
nk cells