Clinical Impact of Pathogenic Germline Variants in Pancreatic Cancer: Results From a Multicenter, Prospective, Universal Genetic Testing Study.

Pedro Luiz Serrano UsÓn JuniorN Jewel SamadderDouglas Riegert-JohnsonLisa BoardmanMitesh J BoradDaniel AhnMohamad B SonbolDouglas O FaigelNorio FukamiRahul PannalaKatie KunzeMichael GolafsharMargaret KlintEdward D EsplinRobert L NussbaumA Keith StewartTanios Bekaii-Saab

Published in: Clinical and translational gastroenterology (2021)

Universal multigene panel testing in PC reveals that 1 in 6 patients are carriers of PGV. Multigene germline testing should be used to aid in treatment selection, prognostication, and familial cancer counseling.

Keyphrases

end stage renal disease
newly diagnosed
chronic kidney disease
dna repair
ejection fraction
prognostic factors
early onset
patient reported outcomes
cross sectional
oxidative stress
dna damage
combination therapy
men who have sex with men
antiretroviral therapy