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MCCMF: collaborative matrix factorization based on matrix completion for predicting miRNA-disease associations.

Tian-Ru WuMeng-Meng YinCui-Na JiaoYing-Lian GaoXiang-Zhen KongJin-Xing Liu
Published in: BMC bioinformatics (2020)
The AUC value of MCCMF is higher than other advanced methods in the fivefold cross validation experiment. In order to comprehensively evaluate the performance of MCCMF, accuracy, precision, recall and f-measure are also added. The final experimental results demonstrate that MCCMF outperforms other methods in predicting miRNA-disease associations. In the end, the effectiveness and practicability of MCCMF are further verified by researching three specific diseases.
Keyphrases
  • randomized controlled trial
  • systematic review
  • quality improvement