PPARδ dysregulation of CCL20/CCR6 axis promotes gastric adenocarcinoma carcinogenesis by remodeling gastric tumor microenvironment.

Yi LiuDaoyan WeiYasunori DeguchiWeiguo XuRui TianFuyao LiuMin XuFei MaoDonghui LiWeidong ChenLovie Ann ValentinEriko DeguchiJames C YaoImad ShureiqiXiangsheng Zuo

Published in: Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association (2023)

PPARδ dysregulation of Ccl20/Ccr6 axis promotes GAC carcinogenesis by remodeling gastric tumor microenvironment. CCL20 might be a potential biomarker for the early detection and progression of GAC.

Keyphrases

liver fibrosis
liver injury
dendritic cells
regulatory t cells
insulin resistance
drug induced
squamous cell carcinoma
fatty acid
type diabetes
radiation therapy
locally advanced