Genomic landscape of malignant phyllodes tumors reveals multiple targetable opportunities.

Oluwadamilola M Fayanju Richard F RiedelEmilia J DiegoAmanda L NashJuneko E Grilley-OlsonNatalie A DanzigerEthan S SokolJeffrey S RossSarah L Sammons

Published in: The oncologist (2024)

In the largest genomic evaluation of MPT to date, multiple clinically actionable mutations were found. Routine sequencing of metastatic MPT may provide additional information to guide treatment decisions and clinical trial enrollment.

Keyphrases

clinical trial
single cell
copy number
squamous cell carcinoma
small cell lung cancer
clinical practice
healthcare
randomized controlled trial
study protocol
health information
health insurance
open label
gene expression
phase iii
smoking cessation
placebo controlled