Relationship Between Low Expressions of tRNA-Derived Fragments with Metastatic Behavior of Colorectal Cancer.
Maryam SahlolbeiFahimeh FattahiSomayeh VafaeiRezvan RajabzadehAref ShiralipourZahra MadjdJafar KianiPublished in: Journal of gastrointestinal cancer (2021)
The present study demonstrated that low expression of tRF/miR-1280, tRNA-ValAAC/CAC, and tRNA-AspGTC was significantly associated with metastatic stage and more aggressive tumor behavior of CRC disease. Our finding promising the potential of using tRFs as biomarkers for cancer diagnosis.