Relationship Between Low Expressions of tRNA-Derived Fragments with Metastatic Behavior of Colorectal Cancer.

Maryam SahlolbeiFahimeh FattahiSomayeh VafaeiRezvan RajabzadehAref ShiralipourZahra MadjdJafar Kiani

Published in: Journal of gastrointestinal cancer (2021)

The present study demonstrated that low expression of tRF/miR-1280, tRNA-ValAAC/CAC, and tRNA-AspGTC was significantly associated with metastatic stage and more aggressive tumor behavior of CRC disease. Our finding promising the potential of using tRFs as biomarkers for cancer diagnosis.

Keyphrases

squamous cell carcinoma
small cell lung cancer
poor prognosis
long non coding rna
cell proliferation
papillary thyroid
young adults
childhood cancer