Protoporphyrin IX (PpIX) Fluorescence during Meningioma Surgery: Correlations with Histological Findings and Expression of Heme Pathway Molecules.

Dorothee C SpilleEva C BunkChristian ThomasZeynep ÖzdemirAndrea WagnerBurak Han Akkurt Manoj MannilWerner PaulusOliver M GrauerWalter StummerVolker SennerBenjamin Brokinkel

Published in: Cancers (2023)

FGR enables the intraoperative identification of meningioma tissue with limitations concerning dura invasion and due to ectopic expression in the CNS. ABCB6, ABCG2, FECH and CPOX are expressed in meningioma tissue and are related to fluorescence.

Keyphrases

poor prognosis
optic nerve
single molecule
minimally invasive
energy transfer
blood brain barrier
acute coronary syndrome
atrial fibrillation
surgical site infection