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Chromogranin A demonstrates higher expression in preeclamptic placentas than in normal pregnancy.

Michalina LisowskaLidia BiesiadaMariusz GrzesiakMagda Rybak-KrzyszkowskaHubert HurasAgnieszka GachTadeusz PietruchaAgata Sakowicz
Published in: BMC pregnancy and childbirth (2021)
This study for the first time reveals that chromogranin A gene expression level is associated with preeclampsia. Moreover, the depletion in catestatin level, which plays a protective role in hypertension development, might be a marker of developing preeclampsia. Further studies may unravel role of Chromogranin A in the discussed disease.
Keyphrases
  • gene expression
  • pregnancy outcomes
  • early onset
  • blood pressure
  • poor prognosis
  • dna methylation
  • preterm birth
  • pregnant women
  • long non coding rna