The Effect of Phenotype and Genotype on the Plasma Proteome in Patients with Inflammatory Bowel Disease.
Arno R BourgonjeShixian HuLieke M SpekhorstDaria V ZhernakovaArnau Vich VilaYanni LiMichiel D VoskuilLisette A van BerkelBrenda Bley FollyMohammed CharroutAhmed MahfouzMarcel J T ReindersJulia I P van HeckLeo A B JoostenMarijn C VisschedijkHendrik M van DullemenKlaas Nico FaberJanneke N SamsomEleonora A M FestenGerard DijkstraRinse K WeersmaPublished in: Journal of Crohn's & colitis (2021)
This study shows that genotype and multiple disease phenotypes strongly associate with the plasma inflammatory proteome in IBD and identifies disease-associated pathways that may help to improve disease management in the future.