Marcel J T Reinders (M J T Reinders, Marcel Reinders)

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 76

Top Topics

Machine Learning

Duchenne Muscular Dystrophy

Patients With Inflammatory Bowel Disease

Top Venues

Nature communications

This page only lists publications with an associated author ORCID identifier.

Publications

Jeppe F Severens, E Onur Karakaslar, Bert A van der Reijden, Elena Sánchez-López, Redmar R van den Berg, Constantijn J M Halkes, Peter van Balen, Joan Hendrik Veelken, Marcel J T Reinders, Marieke Griffioen, Erik Ben van den Akker
Mapping AML heterogeneity - multi-cohort transcriptomic analysis identifies novel clusters and divergent ex-vivo drug responses. Leukemia 38 (4) (2024)
Fatih A Bogaards, T Gehrmann, Marian Beekman, N Lakenberg, Eka H E D Suchiman, Lisette C P G M de Groot, Marcel J T Reinders, Pieternella Eline Slagboom
Secondary integrated analysis of multi-tissue transcriptomic responses to a combined lifestyle intervention in older adults from the GOTO nonrandomized trial. Nature communications 15 (1) (2024)
Jeppe F Severens, E Onur Karakaslar, Bert A van der Reijden, Elena Sánchez-López, Redmar R van den Berg, Constantijn J M Halkes, Peter van Balen, Joan Hendrik Veelken, Marcel J T Reinders, Marieke Griffioen, Erik Ben van den Akker
Mapping AML heterogeneity - multi-cohort transcriptomic analysis identifies novel clusters and divergent ex-vivo drug responses. Leukemia (2024)
Jeppe F Severens, E Onur Karakaslar, Bert A van der Reijden, Elena Sánchez-López, Redmar R van den Berg, Constantijn J M Halkes, Peter van Balen, Joan Hendrik Veelken, Marcel J T Reinders, Marieke Griffioen, Erik Ben van den Akker
Mapping AML heterogeneity - multi-cohort transcriptomic analysis identifies novel clusters and divergent ex-vivo drug responses. Leukemia 38 (4) (2024)
Jeppe F Severens, E Onur Karakaslar, Bert A van der Reijden, Elena Sánchez-López, Redmar R van den Berg, Constantijn J M Halkes, Peter van Balen, Joan Hendrik Veelken, Marcel J T Reinders, Marieke Griffioen, Erik Ben van den Akker
Mapping AML heterogeneity - multi-cohort transcriptomic analysis identifies novel clusters and divergent ex-vivo drug responses. Leukemia 38 (4) (2024)
Fatih A Bogaards, T Gehrmann, Marian Beekman, N Lakenberg, Eka H E D Suchiman, Lisette C P G M de Groot, Marcel J T Reinders, Pieternella Eline Slagboom
Secondary integrated analysis of multi-tissue transcriptomic responses to a combined lifestyle intervention in older adults from the GOTO nonrandomized trial. Nature communications 15 (1) (2024)
Tamim Abdelaal, Laurens M Grossouw, Ronald Jeroen Pasterkamp, Boudewijn P F Lelieveldt, Marcel J T Reinders, Ahmed Mahfouz
SIRV: spatial inference of RNA velocity at the single-cell resolution. NAR genomics and bioinformatics 6 (3) (2024)
Fatih A Bogaards, T Gehrmann, Marian Beekman, N Lakenberg, Eka H E D Suchiman, Lisette C P G M de Groot, Marcel J T Reinders, Pieternella Eline Slagboom
Secondary integrated analysis of multi-tissue transcriptomic responses to a combined lifestyle intervention in older adults from the GOTO nonrandomized trial. Nature communications 15 (1) (2024)
Tamim Abdelaal, Laurens M Grossouw, Ronald Jeroen Pasterkamp, Boudewijn P F Lelieveldt, Marcel J T Reinders, Ahmed Mahfouz
SIRV: spatial inference of RNA velocity at the single-cell resolution. NAR genomics and bioinformatics 6 (3) (2024)
Jeppe F Severens, E Onur Karakaslar, Bert A van der Reijden, Elena Sánchez-López, Redmar R van den Berg, Constantijn J M Halkes, Peter van Balen, Joan Hendrik Veelken, Marcel J T Reinders, Marieke Griffioen, Erik Ben van den Akker
Mapping AML heterogeneity - multi-cohort transcriptomic analysis identifies novel clusters and divergent ex-vivo drug responses. Leukemia (2024)
Pia Keukeleire, Stavros Makrodimitris, Marcel J T Reinders
Cell type deconvolution of methylated cell-free DNA at the resolution of individual reads. NAR genomics and bioinformatics 5 (2) (2023)
Gerard A Bouland, Ahmed Mahfouz, Marcel J T Reinders
Consequences and opportunities arising due to sparser single-cell RNA-seq datasets. Genome biology 24 (1) (2023)
Gerard A Bouland, Ahmed Mahfouz, Marcel J T Reinders
Consequences and opportunities arising due to sparser single-cell RNA-seq datasets. Genome biology 24 (1) (2023)
Daniele Bizzarri, Marcel J T Reinders, Marian Beekman, Pieternella Eline Slagboom, Erik Ben van den Akker, null On Behalf Of The BbmriNl
Technical Report: A Comprehensive Comparison between Different Quantification Versions of Nightingale Health's 1 H-NMR Metabolomics Platform. Metabolites 13 (12) (2023)
Lieke Michielsen, Mohammad Lotfollahi, Daniel Strobl, Lisa Sikkema, Marcel J T Reinders, Fabian Joachim Theis, Ahmed Mahfouz
Single-cell reference mapping to construct and extend cell-type hierarchies. NAR genomics and bioinformatics 5 (3) (2023)
Meng Zhang, Gerard A Bouland, Henne Holstege, Marcel J T Reinders
Identifying Aging and Alzheimer Disease-Associated Somatic Variations in Excitatory Neurons From the Human Frontal Cortex. Neurology. Genetics 9 (3) (2023)
Daniele Bizzarri, Marcel J T Reinders, Marian Beekman, Pieternella Eline Slagboom, Erik Ben van den Akker, null On Behalf Of The BbmriNl
Technical Report: A Comprehensive Comparison between Different Quantification Versions of Nightingale Health's 1 H-NMR Metabolomics Platform. Metabolites 13 (12) (2023)
Tom Mokveld, Zaid Al-Ars, Erik A Sistermans, Marcel J T Reinders
A comprehensive performance analysis of sequence-based within-sample testing NIPT methods. PloS one 18 (4) (2023)
Stavros Makrodimitris, Bram Pronk, Tamim Abdelaal, Marcel J T Reinders
An in-depth comparison of linear and non-linear joint embedding methods for bulk and single-cell multi-omics. Briefings in bioinformatics 25 (1) (2023)
Gerard A Bouland, Ahmed Mahfouz, Marcel J T Reinders
Consequences and opportunities arising due to sparser single-cell RNA-seq datasets. Genome biology 24 (1) (2023)
Meng Zhang, Gerard A Bouland, Henne Holstege, Marcel J T Reinders
Identifying Aging and Alzheimer Disease-Associated Somatic Variations in Excitatory Neurons From the Human Frontal Cortex. Neurology. Genetics 9 (3) (2023)
Gerard A Bouland, Ahmed Mahfouz, Marcel J T Reinders
Consequences and opportunities arising due to sparser single-cell RNA-seq datasets. Genome biology 24 (1) (2023)
Gerard A Bouland, Ahmed Mahfouz, Marcel J T Reinders
Consequences and opportunities arising due to sparser single-cell RNA-seq datasets. Genome biology 24 (1) (2023)
Gerard A Bouland, Ahmed Mahfouz, Marcel J T Reinders
Consequences and opportunities arising due to sparser single-cell RNA-seq datasets. Genome biology 24 (1) (2023)
Niccolo' Tesi, Sven van der Lee, Marc Hulsman, Henne Holstege, Marcel J T Reinders
Bioinformatics Strategies for the Analysis and Integration of Large-Scale Multiomics Data. The journals of gerontology. Series A, Biological sciences and medical sciences 78 (4) (2023)
Daniele Bizzarri, Marcel J T Reinders, Marian Beekman, Pieternella Eline Slagboom, Erik Ben van den Akker, null On Behalf Of The BbmriNl
Technical Report: A Comprehensive Comparison between Different Quantification Versions of Nightingale Health's 1 H-NMR Metabolomics Platform. Metabolites 13 (12) (2023)
Akash Singh, Kirti Biharie, Marcel J T Reinders, Ahmed Mahfouz, Tamim Abdelaal
scTopoGAN: unsupervised manifold alignment of single-cell data. Bioinformatics advances 3 (1) (2023)
Michiel Bongaerts, Purva Kulkarni, Alan Zammit, Ramon Bonte, Leo A J Kluijtmans, Henk J Blom, Udo F H Engelke, David M J Tax, George J G Ruijter, Marcel J T Reinders
Benchmarking Outlier Detection Methods for Detecting IEM Patients in Untargeted Metabolomics Data. Metabolites 13 (1) (2023)
Kirti Biharie, Lieke Michielsen, Marcel J T Reinders, Ahmed Mahfouz
Cell type matching across species using protein embeddings and transfer learning. Bioinformatics (Oxford, England) 39 (39 Suppl 1) (2023)
Gerard A Bouland, Ahmed Mahfouz, Marcel J T Reinders
Consequences and opportunities arising due to sparser single-cell RNA-seq datasets. Genome biology 24 (1) (2023)
Michiel Bongaerts, Purva Kulkarni, Alan Zammit, Ramon Bonte, Leo A J Kluijtmans, Henk J Blom, Udo F H Engelke, David M J Tax, George J G Ruijter, Marcel J T Reinders
Benchmarking Outlier Detection Methods for Detecting IEM Patients in Untargeted Metabolomics Data. Metabolites 13 (1) (2023)
Marie de Bakker, Teun B Petersen, Anja J Rueten-Budde, K Martijn Akkerhuis, Victor A Umans, Jasper J Brugts, Tjeerd Germans, Marcel J T Reinders, Peter D Katsikis, Peter J van der Spek, Rachel Ostroff, Ruicong She, David E Lanfear, Folkert W Asselbergs, Eric Boersma, Dimitris Rizopoulos, Isabella Kardys
Machine learning-based biomarker profile derived from 4210 serially measured proteins predicts clinical outcome of patients with heart failure. European heart journal. Digital health 4 (6) (2023)
Jim M Smit, Jesse H Krijthe, W M R Kant, J A Labrecque, M Komorowski, D A M P J Gommers, J van Bommel, Marcel J T Reinders, Michel E Van Genderen
Causal inference using observational intensive care unit data: a scoping review and recommendations for future practice. NPJ digital medicine 6 (1) (2023)
Michiel Bongaerts, Purva Kulkarni, Alan Zammit, Ramon Bonte, Leo A J Kluijtmans, Henk J Blom, Udo F H Engelke, David M J Tax, George J G Ruijter, Marcel J T Reinders
Benchmarking Outlier Detection Methods for Detecting IEM Patients in Untargeted Metabolomics Data. Metabolites 13 (1) (2023)
Lieke M Kuiper, Harmke A Polinder-Bos, Daniele Bizzarri, Dina Vojinovic, Costanza L Vallerga, Marian Beekman, Martijn E T Dollé, Mohsen Ghanbari, Trudy G Voortman, Marcel J T Reinders, W M Monique Verschuren, P Eline Slagboom, Erik Ben van den Akker, Joyce B J van Meurs
Epigenetic and Metabolomic Biomarkers for Biological Age: A Comparative Analysis of Mortality and Frailty Risk. The journals of gerontology. Series A, Biological sciences and medical sciences (2023)
Henne Holstege, Marc Hulsman, Camille Charbonnier, Benjamin Grenier-Boley, Olivier Quenez, Detelina Grozeva, Jeroen G J van Rooij, Rebecca Sims, Shahzad Ahmad, Ivana Nedeljković, Penny J Norsworthy, Oriol Dols-Icardo, Holger Hummerich, Amit Kawalia, Phillippe Amouyel, Gary W Beecham, Claudine Berr, Joshua C Bis, Anne Boland, Paola Bossù, Femke Bouwman, Jose Bras, Dominique Campion, Jesse Nicholas Cochran, Antonio Daniele, Jean-François Dartigues, Stephanie Debette, Jean-François Deleuze, Nicola Denning, Anita L DeStefano, Lindsay A Farrer, Maria Victoria Fernandez, Nick C Fox, Daniela Galimberti, French Exome Consortium, Johan J P Gille, Yann Le Guen, Rita Guerreiro, Jonathan L Haines, Clive Holmes, Mohammad Arfan Ikram, M Kamran Ikram, Iris E Jansen, Robert Kraaij, Marc Lathrop, Afina W Lemstra, Alberto Lleó, Lauren Luckcuck, Marcel M A M Mannens, Rachel Marshall, Eden R Martin, Carlo Masullo, Richard Mayeux, Patrizia Mecocci, Alun Meggy, Merel O Mol, Kevin Morgan, Richard M Myers, Benedetta Nacmias, Adam C Naj, Valerio Napolioni, Florence Pasquier, Pau Pastor, Margaret A Pericak-Vance, Rachel Raybould, Richard Redon, Marcel J T Reinders, Anne-Claire Richard, Steffi G Riedel-Heller, Fernando Rivadeneira, Stéphane Rousseau, Natalie S Ryan, Salha Saad, Pascual Sánchez Juan, Gerard D Schellenberg, Philip Scheltens, Jonathan M Schott, Davide Seripa, Sudha Seshadri, Daoud Sie, Erik A Sistermans, Sandro Sorbi, Rosalina M L van Spaendonk, Gianfranco Spalletta, Niccolo' Tesi, Betty Tijms, Andre G Uitterlinden, Sven J Van der Lee, Pieter Jelle Visser, Michael Wagner, David Wallon, Li-San Wang, Aline Zarea, Jordi Clarimon, John C van Swieten, Michael D Greicius, Jennifer S Yokoyama, Carlos Cruchaga, John Hardy, Alfredo Ramirez, Simon Mead, Wiesje Maria van der Flier, Cornelia M Van Duijn, Julie Williams, Gaël Nicolas, Celine Bellenguez, Jean-Charles Lambert
Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as risk factors for Alzheimer's disease. Nature genetics 54 (12) (2022)
Mostafa Eltager, Tamim Abdelaal, Ahmed Mahfouz, Marcel J T Reinders
scMoC: single-cell multi-omics clustering. Bioinformatics advances 2 (1) (2022)
Martijn Cordes, Kirsten Canté-Barrett, Erik Ben van den Akker, Federico Andrea Moretti, Szymon M Kiełbasa, Sandra A Vloemans, Laura Garcia-Perez, Cristina Teodosio, Jacques J M van Dongen, Karin Pike-Overzet, Marcel J T Reinders, Frank J T Staal
Single-cell immune profiling reveals thymus-seeding populations, T cell commitment, and multilineage development in the human thymus. Science immunology 7 (77) (2022)
Mostafa Eltager, Tamim Abdelaal, Ahmed Mahfouz, Marcel J T Reinders
scMoC: single-cell multi-omics clustering. Bioinformatics advances 2 (1) (2022)
Daniele Bizzarri, Marcel J T Reinders, M Beekman, P E Slagboom, E B van den Akker
MiMIR: R-shiny application to infer risk factors and endpoints from Nightingale Health's 1H-NMR metabolomics data. Bioinformatics (Oxford, England) 38 (15) (2022)
Federico Ferraro, Christina Fevga, Vincenzo Bonifati, Wim Mandemakers, Ahmed Mahfouz, Marcel J T Reinders
Correcting Differential Gene Expression Analysis for Cyto-Architectural Alterations in Substantia Nigra of Parkinson's Disease Patients Reveals Known and Potential Novel Disease-Associated Genes and Pathways. Cells 11 (2) (2022)
Skander Tahar Mulder, Amir-Houshang Omidvari, Anja J Rueten-Budde, Pei-Hua Huang, Ki-Hun Kim, Babette Bais, Melek Rousian, Rihan Hai, Can Akgun, Jeanine E Roeters van Lennep, Sten Paul Willemsen, Peter R Rijnbeek, David M J Tax, Marcel J T Reinders, Eric Boersma, Dimitris Rizopoulos, Valentijn T Visch, Régine Patricia Maria Steegers-Theunissen
Dynamic Digital Twin: Diagnosis, Treatment, Prediction, and Prevention of Disease During the Life Course. Journal of medical Internet research 24 (9) (2022)
Soufiane M C Mourragui, Marco Loog, Daniel J Vis, Kat Moore, Anna G Manjon, Mark A van de Wiel, Marcel J T Reinders, Lodewyk F A Wessels
Predicting patient response with models trained on cell lines and patient-derived xenografts by nonlinear transfer learning. Proceedings of the National Academy of Sciences of the United States of America 118 (49) (2022)
Arman Naseri Jahfari, David M J Tax, Marcel J T Reinders, Ivo van der Bilt
Machine Learning for Cardiovascular Outcomes From Wearable Data: Systematic Review From a Technology Readiness Level Point of View. JMIR medical informatics 10 (1) (2022)
Celine Bellenguez, Fahri Küçükali, Iris E Jansen, Luca Kleineidam, Sonia Moreno-Grau, Ivana Nedeljković, Adam C Naj, Rafael Campos-Martin, Benjamin Grenier-Boley, Victor Andrade, Peter A Holmans, Anne Boland, Vincent Damotte, Sven J Van der Lee, Marcos Romualdo Costa, Teemu Kuulasmaa, Qiong Yang, Itziar De Rojas, Joshua C Bis, Amber Yaqub, Ivana Prokic, Julien Chapuis, Shahzad Ahmad, Vilmantas Giedraitis, Dag Aarsland, Pablo García González, Carla Abdelnour, Emilio Alarcón-Martín, Daniel Alcolea, Montserrat Alegret, Ignacio Alvarez, Victoria Álvarez, Nicola J Armstrong, Anthoula C Tsolaki, Carmen Antúnez, Ildebrando Appollonio, Marina Arcaro, Silvana Archetti, Alfonso Arias Pastor, Beatrice Arosio, Lavinia Athanasiu, Henri Bailly, Nerisa Banaj, Miguel Baquero, Sandra Barral, Alexa Beiser, Ana Belén Pastor, Jennifer E Below, Penelope Benchek, Luisa Benussi, Claudine Berr, Céline Besse, Valentina Bessi, Giuliano Binetti, Alessandra Bizarro, Rafael Blesa, Merce Boada, Eric Boerwinkle, Barbara Borroni, Silvia Boschi, Paola Bossù, Geir Bråthen, Jan Bressler, Catherine Bresner, Henry Brodaty, Keeley J Brookes, Luis Ignacio Brusco, Dolores Buiza-Rueda, Katharina Bûrger, Vanessa Burholt, William S Bush, Miguel Calero Lara, Laura B Cantwell, Geneviève Chene, Jaeyoon Chung, Michael L Cuccaro, Ángel Carracedo, Roberta Cecchetti, Laura Cervera-Carles, Camille Charbonnier, Hung-Hsin Chen, Caterina Chillotti, Simona Ciccone, Jurgen A H R Claassen, Christopher Clark, Elisa Conti, Anaïs Corma-Gómez, Emanuele Costantini, Carlo Custodero, Delphine Daian, Maria Carolina Dalmasso, Antonio Daniele, Efthimios Dardiotis, Jean-François Dartigues, Peter Paul de Deyn, Katia de Paiva Lopes, Lotje D de Witte, Stephanie Debette, Jürgen Deckert, Teodoro Del Ser, Nicola Denning, Anita DeStefano, Martin Dichgans, Janine Diehl-Schmid, Mónica Diez-Fairen, Paolo Dionigi Rossi, Srdjan Djurovic, Emmanuelle Duron, Emrah Düzel, Carole Dufouil, Gudny Eiriksdottir, Sebastiaan Engelborghs, Valentina Escott-Price, Ana Espinosa, Michael Ewers, Kelley M Faber, Tagliavini Fabrizio, Sune Fallgaard Nielsen, David W Fardo, Lucia Farotti, Chiara Fenoglio, Marta Fernández-Fuertes, Raffaele Ferrari, Catarina B Ferreira, Evelyn Ferri, Bertrand Fin, Peter Fischer, Tormod Fladby, Klaus Fließbach, Bernard Fongang, Myriam Fornage, Juan Fortea, Tatiana M Foroud, Silvia Fostinelli, Nick C Fox, Emlio Franco-Macías, Maria Jesus Bullido, Ana Frank-García, Lutz Froelich, Brian Fulton-Howard, Daniela Galimberti, Jose Maria García-Alberca, Pablo García-González, Sebastian Garcia-Madrona, Guillermo Garcia-Ribas, Roberta Ghidoni, Ina Giegling, Giaccone Giorgio, Alison Mary Goate, Oliver Goldhardt, Duber Gomez-Fonseca, Antonio Gonzalez Perez, Caroline Graff, Giulia Grande, Emma Green, Timo Grimmer, Edna Grünblatt, Michelle Grunin, Vilmundur G Gudnason, Tamar Guetta-Baranes, Annakaisa Haapasalo, Georgios Hadjigeorgiou, Jonathan L Haines, Kara L Hamilton-Nelson, Harald Hampel, Olivier Hanon, John Hardy, Annette M Hartmann, Lucrezia Hausner, Janet C Harwood, Stefanie Heilmann-Heimbach, Seppo Helisalmi, Michael T Heneka, Isabel Hernández, Martin J Herrmann, Per Hoffmann, Clive Holmes, Henne Holstege, Raquel Huerto Vilas, Marc Hulsman, Jack Humphrey, Geert Jan Biessels, Xueqiu Jian, Charlotte Johansson, Gyungah R Jun, Yuriko Katsumata, John Kauwe, Patrick Gavin Kehoe, Lena Kilander, Anne Kinhult Ståhlbom, Miia Kivipelto, Anne Koivisto, Kornhuber Johannes, Mary H Kosmidis, Walter A Kukull, Pavel P Kuksa, Brian W Kunkle, Amanda B Kuzma, Carmen Lage, Erika J Laukka, Lenore J Launer, Alessandra Lauria, Chien-Yueh Lee, Jenni Lehtisalo, Ondrej Lerch, Alberto Lleó, William Longstreth, Oscar L Lopez, Adolfo Lopez de Munain, Seth Love, Malin Löwemark, Lauren Luckcuck, Kathryn L Lunetta, Yiyi Ma, Juan Macías, Catherine Anne MacLeod, Wolfgang Maier, Francesca Mangialasche, Marco Spallazzi, Marta Marquié, Rachel Marshall, Eden R Martin, Angel Martín Montes, Carmen Martínez Rodríguez, Carlo Masullo, Richard Mayeux, Simon Mead, Patrizia Mecocci, Miguel Medina Padilla, Alun Meggy, Shima Mehrabian, Silvia Mendoza, Menéndez-González Manuel, Pablo Mir, Susanne Moebus, Merel O Mol, Laura Molina-Porcel, Laura Montrreal, Laura Morelli, Fermin Moreno, Kevin Morgan, Thomas Mosley, Markus Maria Nöthen, Carolina Muchnik, Shubhabrata Mukherjee, Benedetta Nacmias, Tiia Ngandu, Gaël Nicolas, Børge Grønne Nordestgaard, Robert Olaso, Adelina Orellana, Michela Orsini, Gemma Ortega, Alessandro Padovani, Caffarra Paolo, Goran Papenberg, Lucilla Parnetti, Florence Pasquier, Pau Pastor, Gina M Peloso, Alba Pérez-Cordón, Jordi Pérez Tur, Pierre Pericard, Oliver Peters, Yolande A L Pijnenburg, Juan Antonio Pineda, Gerard Piñol-Ripoll, Claudia Pisanu, Thomas Polak, Julius Popp, Danielle Posthuma, Josef Priller, Raquel Puerta, Olivier Quenez, Inés Quintela, Jesper Qvist Thomassen, Alberto Rábano, Innocenzo Rainero, Farid Rajabli, Inez Ramakers, Luis Miguel Real, Marcel J T Reinders, Christiane Reitz, Dolly Reyes-Dumeyer, Perry Ridge, Steffi G Riedel-Heller, Peter Riederer, Natalia Roberto, Eloy Rodríguez-Rodríguez, Arvid Rongve, Irene Rosas Allende, Maitée Rosende-Roca, Jose Luis Royo, Elisa Rubino, Dan Rujescu, María Eugenia Sáez, Paraskevi Sakka, Ingvild Saltvedt, Ángela Sanabria, María Bernal Sánchez-Arjona, Florentino Sanchez-Garcia, Pascual Sánchez Juan, Raquel Sánchez-Valle, Sigrid B Sando, Chloe Sarnowski, Claudia L Satizabal, Michela Scamosci, Nikolaos Scarmeas, Elio Scarpini, Philip Scheltens, Norbert Scherbaum, Martin Scherer, Matthias Schmid, Anja Schneider, Jonathan M Schott, Geir Selbaek, Davide Seripa, Manuel Serrano, Jin Sha, Alexey A Shadrin, Olivia Skrobot, Susan Slifer, Gijsje J L Snijders, Hilkka Soininen, Vincenzo Solfrizzi, Alina Solomon, Yeunjoo E Song, Sandro Sorbi, Oscar Sotolongo, Gianfranco Spalletta, Annika Spottke, Alessio Squassina, Eystein Stordal, Juan Pablo Tartan, Lluís Tárraga, Niccolo Tesí, Anbupalam Thalamuthu, Tegos Thomas, Giuseppe Tosto, Latchezar Traykov, Lucio Tremolizzo, Anne Tybjærg-Hansen, Andre G Uitterlinden, Abbe Ullgren, Ingun Ulstein, Sergi Valero, Otto Valladares, Christine Van Broeckhoven, Jeffery Vance, Badri N Vardarajan, Aad van der Lugt, Jasper Van Dongen, Jeroen van Rooij, John van Swieten, Rik Vandenberghe, Frans Verhey, Jean-Sébastien Vidal, Jonathan S Vogelgsang, Martin Vyhnalek, Michael Wagner, David Wallon, Li-San Wang, Ruiqi Wang, Leonie Weinhold, Jens Wiltfang, Gill Windle, Robert T Woods, Mary Yannakoulia, Habil Zare, Yi Zhao, Xiaoling Zhang, Congcong Zhu, Miren Zulaica, null null, null null, null null, null null, null null, null null, null null, null null, null null, Lindsay A Farrer, Bruce M Psaty, Mohsen Ghanbari, Towfique Raj, Perminder Singh Sachdev, Karen A Mather, Frank Jessen, Mohammad Arfan Ikram, Alexandre de Mendonça, Jakub Hort, Magdalini Tsolaki, Margaret A Pericak-Vance, Phillippe Amouyel, Julie Williams, Ruth Frikke-Schmidt, Jordi Clarimon, Jean-François Deleuze, Giacomina Rossi, Sudha Seshadri, Ole Andreas Andreassen, Martin Ingelsson, Mikko Hiltunen, Kristel Sleegers, Gerard D Schellenberg, Cornelia M Van Duijn, Rebecca Sims, Wiesje Maria van der Flier, Agustín Ruiz, Alfredo Ramirez, Jean-Charles Lambert
New insights into the genetic etiology of Alzheimer's disease and related dementias. Nature genetics 54 (4) (2022)
Fatih A Bogaards, Thies Gehrmann, Marian Beekman, Erik Ben van den Akker, Ondine van de Rest, Roland Willem Jan van Hangelbroek, Raymond Noordam, Simon Pieter Mooijaart, Lisette C P G M de Groot, Marcel J T Reinders, Pieternella Eline Slagboom
PLIS: A metabolomic response monitor to a lifestyle intervention study in older adults. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 36 (11) (2022)
Lianne Maria Reus, Iris E Jansen, Merel O Mol, Fred van Ruissen, Jeroen G J van Rooij, Natasja M van Schoor, Niccolo' Tesi, Marcel J T Reinders, Martijn A Huisman, Henne Holstege, Pieter Jelle Visser, Sterre C M de Boer, Marc Hulsman, Shahzad Ahmad, Ivana Nedeljković, Andre G Uitterlinden, Mohammad Arfan Ikram, Cornelia M Van Duijn, Harro Seelaar, Inez H G B Ramakers, Frans R J Verhey, Aad van der Lugt, Jurgen A H R Claassen, Geert Jan Biessels, Peter Paul De Deyn, Philip Scheltens, Wiesje Maria van der Flier, John C van Swieten, Yolande A L Pijnenburg, Sven J Van der Lee
Genome-wide association study of frontotemporal dementia identifies a C9ORF72 haplotype with a median of 12-G4C2 repeats that predisposes to pathological repeat expansions. Translational psychiatry 11 (1) (2021)
Indu Khatri, Magdalena A Berkowska, Erik B van den Akker, Cristina Teodosio, Marcel J T Reinders, Jacques J M van Dongen
Reply to the Commentary on population matched (pm) germline allelic variants of immunoglobulin (IG) loci: relevance in infectious diseases and vaccination studies in human populations. Genes and immunity (2021)
Indu Khatri, Annieck M Diks, Erik Ben van den Akker, Liesbeth E M Oosten, Jaap Jan Zwaginga, Marcel J T Reinders, Jacques J M van Dongen, Magdalena A Berkowska
Longitudinal Dynamics of Human B-Cell Response at the Single-Cell Level in Response to Tdap Vaccination. Vaccines 9 (11) (2021)
Arno R Bourgonje, Shixian Hu, Lieke M Spekhorst, Daria V Zhernakova, Arnau Vich Vila, Yanni Li, Michiel D Voskuil, Lisette A van Berkel, Brenda Bley Folly, Mohammed Charrout, Ahmed Mahfouz, Marcel J T Reinders, Julia I P van Heck, Leo A B Joosten, Marijn C Visschedijk, Hendrik M van Dullemen, Klaas Nico Faber, Janneke N Samsom, Eleonora A M Festen, Gerard Dijkstra, Rinse K Weersma
The Effect of Phenotype and Genotype on the Plasma Proteome in Patients with Inflammatory Bowel Disease. Journal of Crohn's & colitis (2021)
Tom Mokveld, Zaid Al-Ars, Erik A Sistermans, Marcel J T Reinders
WisecondorFF: Improved Fetal Aneuploidy Detection from Shallow WGS through Fragment Length Analysis. Diagnostics (Basel, Switzerland) 12 (1) (2021)
Jim M Smit, Michel E Van Genderen, Marcel J T Reinders, Diederik A M P J Gommers, Jesse H Krijthe, Rita J G van den Berg-Emons
Demystifying machine learning for mortality prediction. Critical care (London, England) 25 (1) (2021)
Lieke Michielsen, Marcel J T Reinders, Ahmed Mahfouz
Hierarchical progressive learning of cell identities in single-cell data. Nature communications 12 (1) (2021)
Gerard A Bouland, Ahmed Mahfouz, Marcel J T Reinders
Differential analysis of binarized single-cell RNA sequencing data captures biological variation. NAR genomics and bioinformatics 3 (4) (2021)
Sanne E de Jong, Vincent van Unen, Mikhael D Manurung, Koen Alexander Stam, Jelle J Goeman, Simon P Jochems, Thomas Höllt, Nicola Pezzotti, Yoanne D Mouwenda, Madeleine Eunice Betouke Ongwe, Freia-Raphaella Lorenz, Yvonne C M Kruize, Shohreh Azimi, Marion H König, Anna Vilanova, Elmar Eisemann, Boudewijn P F Lelieveldt, Meta Roestenberg, B Kim Lee Sim, Marcel J T Reinders, Rolf Fendel, Stephen L Hoffman, Peter G Kremsner, Frits Koning, Benjamin Mordmüller, Bertrand Lell, Maria M Yazdanbakhsh
Systems analysis and controlled malaria infection in Europeans and Africans elucidate naturally acquired immunity. Nature immunology 22 (5) (2021)
Joris Deelen, Daniel S Evans, Dan E Arking, Niccolo' Tesi, Marianne Nygaard, Xiaomin Liu, Mary K Wojczynski, Mary L Biggs, Ashley van der Spek, Gil Atzmon, Erin B Ware, Chloé Sarnowski, Albert V Smith, Ilkka Seppälä, Heather J Cordell, Janina Dose, Najaf Amin, Alice M Arnold, Kristin L Ayers, Nir Barzilai, Elizabeth J Becker, Marian Beekman, Hélène Blanché, Kaare Christensen, Lene Christiansen, Joanna C Collerton, Sarah Cubaynes, Steven R Cummings, Karen Davies, Birgit Debrabant, Jean-François Deleuze, Rachel Duncan, Jessica D Faul, Claudio Franceschi, Pilar Galan, Vilmundur G Gudnason, Tamara B Harris, Martijn Huisman, Mikko A Hurme, Carol Jagger, Iris Jansen, Marja Jylhä, Mika Kähönen, David Karasik, Sharon L R Kardia, Andrew Kingston, Thomas B L Kirkwood, Lenore J Launer, Terho Lehtimäki, Wolfgang Lieb, Leo-Pekka Lyytikäinen, Carmen Martín-Ruiz, Junxia Min, Almut Nebel, Anne B Newman, Chao Nie, Ellen A Nohr, Eric S Orwoll, Thomas T Perls, Michael A Province, Bruce M Psaty, Olli T Raitakari, Marcel J T Reinders, Jean Marie Robine, Jerome I Rotter, Paola Sebastiani, Jennifer A Smith, Thorkild I A Sørensen, Kent D Taylor, Andre G Uitterlinden, Wiesje van der Flier, Sven J Van der Lee, Cornelia M van Duijn, Diana van Heemst, James W Vaupel, David R Weir, Kenny Ye, Yi Zeng, Wanlin Zheng, Henne Holstege, Douglas P Kiel, Kathryn L Lunetta, P Eline Slagboom, Joanne M Murabito
Publisher Correction: A meta-analysis of genome-wide association studies identifies multiple longevity genes. Nature communications 12 (1) (2021)
Nathalie Groen, Floris Leenders, Ahmed Mahfouz, Amadeo Muñoz Garcia, Mauro J Muraro, Natascha de Graaf, Ton J Rabelink, Wytske M van Weerden, Alexander van Oudenaarden, Arnaud Zaldumbide, Marcel J T Reinders, Eelco J P de Koning, Francoise Carlotti
Single-Cell Transcriptomics Links Loss of Human Pancreatic β-Cell Identity to ER Stress. Cells 10 (12) (2021)
Niccolo' Tesi, Sven van der Lee, Marc Hulsman, Henne Holstege, Marcel J T Reinders
snpXplorer: a web application to explore human SNP-associations and annotate SNP-sets. Nucleic acids research 49 (W1) (2021)
Arlin Keo, Oleh Dzyubachyk, Jeroen van der Grond, Anne Hafkemeijer, Wilma D J Van de Berg, Jacobus J van Hilten, Marcel J T Reinders, Ahmed Mahfouz
Cingulate networks associated with gray matter loss in Parkinson's disease show high expression of cholinergic genes in the healthy brain. The European journal of neuroscience 53 (11) (2021)
Jasper Linthorst, Wim Meert, Matthew S Hestand, Jonas Korlach, Joris Robert Vermeesch, Marcel J T Reinders, Henne Holstege
Extreme enrichment of VNTR-associated polymorphicity in human subtelomeres: genes with most VNTRs are predominantly expressed in the brain. Translational psychiatry 10 (1) (2020)
Niccolo' Tesi, Sven J van der Lee, Marc Hulsman, Iris E Jansen, Najada Stringa, Natasja M van Schoor, Philip Scheltens, Wiesje M van der Flier, Martijn Huisman, Marcel J T Reinders, Henne Holstege
Immune response and endocytosis pathways are associated with the resilience against Alzheimer's disease. Translational psychiatry 10 (1) (2020)
Stavros Makrodimitris, Roeland C H J van Ham, Marcel J T Reinders
Automatic Gene Function Prediction in the 2020's. Genes 11 (11) (2020)
Erik Ben van den Akker, Stavros Makrodimitris, Marc Hulsman, Martijn H Brugman, Tatjana Nikolic, Ted Bradley, Quinten Waisfisz, Frank Baas, Marja E Jakobs, Daphne de Jong, P Eline Slagboom, Frank J T Staal, Marcel J T Reinders, Henne Holstege
Dynamic clonal hematopoiesis and functional T-cell immunity in a supercentenarian. Leukemia 35 (7) (2020)
Arlin Keo, Ahmed Mahfouz, Angela M T Ingrassia, Jean-Pascal Meneboo, Celine Villenet, Eugénie Mutez, Thomas Comptdaer, Boudewijn P F Lelieveldt, Martin Figeac, Marie-Christine Chartier-Harlin, Wilma D J Van de Berg, Jacobus J van Hilten, Marcel J T Reinders
Transcriptomic signatures of brain regional vulnerability to Parkinson's disease. Communications biology 3 (1) (2020)
Tjardo D Maarseveen, Timo Meinderink, Marcel J T Reinders, Johannes Knitza, Thomas Wj Huizinga, Arnd Kleyer, David Simon, Erik Ben van den Akker, Rachel Knevel
Machine Learning Electronic Health Record Identification of Patients with Rheumatoid Arthritis: Algorithm Pipeline Development and Validation Study. JMIR medical informatics 8 (11) (2020)
Michiel Bongaerts, Ramon Bonte, Serwet Demirdas, Edwin H Jacobs, Esmee Oussoren, Ans T van der Ploeg, Margreet A E M Wagenmakers, Robert M W Hofstra, Henk J Blom, Marcel J T Reinders, George J G Ruijter
Using Out-of-Batch Reference Populations to Improve Untargeted Metabolomics for Screening Inborn Errors of Metabolism. Metabolites 11 (1) (2020)
Christian Groß, Chiara Bortoluzzi, Dick de Ridder, Hendrik-Jan Megens, Martien A M Groenen, Marcel J T Reinders, Mirte Bosse
Prioritizing sequence variants in conserved non-coding elements in the chicken genome using chCADD. PLoS genetics 16 (9) (2020)
Joris Deelen, Daniel S Evans, Dan E Arking, Niccolo' Tesi, Marianne Nygaard, Xiaomin Liu, Mary K Wojczynski, Mary L Biggs, Ashley van der Spek, Gil Atzmon, Erin B Ware, Chloé Sarnowski, Albert V Smith, Ilkka Seppälä, Heather J Cordell, Janina Dose, Najaf Amin, Alice M Arnold, Kristin L Ayers, Nir Barzilai, Elizabeth J Becker, Marian Beekman, Hélène Blanché, Kaare Christensen, Lene Christiansen, Joanna C Collerton, Sarah Cubaynes, Steven R Cummings, Karen Davies, Birgit Debrabant, Jean-François Deleuze, Rachel Duncan, Jessica D Faul, Claudio Franceschi, Pilar Galan, Vilmundur G Gudnason, Tamara B Harris, Martijn Huisman, Mikko A Hurme, Carol Jagger, Iris Jansen, Marja Jylhä, Mika Kähönen, David Karasik, Sharon L R Kardia, Andrew Kingston, Thomas B L Kirkwood, Lenore J Launer, Terho Lehtimäki, Wolfgang Lieb, Leo-Pekka Lyytikäinen, Carmen Martín-Ruiz, Junxia Min, Almut Nebel, Anne B Newman, Chao Nie, Ellen A Nohr, Eric S Orwoll, Thomas T Perls, Michael A Province, Bruce M Psaty, Olli T Raitakari, Marcel J T Reinders, Jean Marie Robine, Jerome I Rotter, Paola Sebastiani, Jennifer A Smith, Thorkild I A Sørensen, Kent D Taylor, Andre G Uitterlinden, Wiesje van der Flier, Sven J Van der Lee, Cornelia M van Duijn, Diana van Heemst, James W Vaupel, David R Weir, Kenny Ye, Yi Zeng, Wanlin Zheng, Henne Holstege, Douglas P Kiel, Kathryn L Lunetta, P Eline Slagboom, Joanne M Murabito
A meta-analysis of genome-wide association studies identifies multiple longevity genes. Nature communications 10 (1) (2019)
Nathalie Doorenweerd, Ahmed Mahfouz, Maaike van Putten, Rajaram Kaliyaperumal, Peter A C T' Hoen, Jos G M Hendriksen, Annemieke M Aartsma-Rus, Jan J G M Verschuuren, Erik H Niks, Marcel J T Reinders, Hermien E Kan, Boudewijn P F Lelieveldt
Author Correction: Timing and localization of human dystrophin isoform expression provide insights into the cognitive phenotype of Duchenne muscular dystrophy. Scientific reports 8 (1) (2018)
Thies Gehrmann, Jordi F Pelkmans, Robin A Ohm, Aurin M Vos, Anton S M Sonnenberg, Johan J P Baars, Han A B Wösten, Marcel J T Reinders, Thomas Abeel
Nucleus-specific expression in the multinuclear mushroom-forming fungus Agaricus bisporus reveals different nuclear regulatory programs. Proceedings of the National Academy of Sciences of the United States of America 115 (17) (2018)
Niccolò Tesi, Sven J van der Lee, Marc Hulsman, Iris E Jansen, Najada Stringa, Natasja van Schoor, Hanne Meijers-Heijboer, Martijn Huisman, Philip Scheltens, Marcel J T Reinders, Wiesje M van der Flier, Henne Holstege
Centenarian controls increase variant effect sizes by an average twofold in an extreme case-extreme control analysis of Alzheimer's disease. European journal of human genetics : EJHG 27 (2) (2018)
Roy Straver, Marjan M Weiss, Quinten Waisfisz, Erik A Sistermans, Marcel J T Reinders
WISExome: a within-sample comparison approach to detect copy number variations in whole exome sequencing data. European journal of human genetics : EJHG 25 (12) (2017)
Vincent van Unen, Thomas Höllt, Nicola Pezzotti, Na Li, Marcel J T Reinders, Elmar Eisemann, Frits Koning, Anna Vilanova, Boudewijn P F Lelieveldt
Visual analysis of mass cytometry data by hierarchical stochastic neighbour embedding reveals rare cell types. Nature communications 8 (1) (2017)
Nathalie Doorenweerd, Ahmed Mahfouz, Maaike van Putten, Rajaram Kaliyaperumal, Peter A C T' Hoen, Jos G M Hendriksen, Annemieke M Aartsma-Rus, Jan J G M Verschuuren, Erik H Niks, Marcel J T Reinders, Hermien E Kan, Boudewijn P F Lelieveldt
Timing and localization of human dystrophin isoform expression provide insights into the cognitive phenotype of Duchenne muscular dystrophy. Scientific reports 7 (1) (2017)
Ahmed Mahfouz, Boudewijn P F Lelieveldt, Aldo Grefhorst, Lisa T C M van Weert, Isabel M Mol, Hetty C M Sips, José K van den Heuvel, Nicole A Datson, Jenny A Visser, Marcel J T Reinders, Onno C Meijer
Genome-wide coexpression of steroid receptors in the mouse brain: Identifying signaling pathways and functionally coordinated regions. Proceedings of the National Academy of Sciences of the United States of America 113 (10) (2016)
Walid M Abdelmoula, Benjamin Balluff, Sonja Englert, Jouke Dijkstra, Marcel J T Reinders, Axel Walch, Liam A McDonnell, Boudewijn P F Lelieveldt
Data-driven identification of prognostic tumor subpopulations using spatially mapped t-SNE of mass spectrometry imaging data. Proceedings of the National Academy of Sciences of the United States of America 113 (43) (2016)