Sevoflurane for Sedation in Acute Respiratory Distress Syndrome. A Randomized Controlled Pilot Study.

Matthieu JabaudonPierre BoucherEtienne ImhoffRussell ChabanneJean-Sébastien FaureLaurence RoszykSandrine ThibaultRaiko BlondonnetGael ClairefondRenaud GuérinSébastien PerbetSophie CayotThomas GodetBruno PereiraVincent SapinJean-Etienne BazinEmmanuel FutierJean-Michel Constantin

Published in: American journal of respiratory and critical care medicine (2017)

In patients with ARDS, use of inhaled sevoflurane improved oxygenation and decreased levels of a marker of epithelial injury and of some inflammatory markers, compared with midazolam. Clinical trial registered with www.clinicaltrials.gov (NCT 02166853).

Keyphrases

acute respiratory distress syndrome
mechanical ventilation
clinical trial
extracorporeal membrane oxygenation
cystic fibrosis
phase ii
study protocol
double blind
intensive care unit
randomized controlled trial