Regulation of osteogenesis via miR-101-3p in mesenchymal stem cells by human gingival fibroblasts.

Eri Kaneda-IkedaTomoyuki IwataNoriyoshi MizunoTakayoshi NagaharaMikihito KajiyaKazuhisa OuharaMinami YoshiokaShu IshidaHiroyuki KawaguchiHidemi Kurihara

Published in: Journal of bone and mineral metabolism (2020)

Humoral factors from HGF suppressed osteogenesis in MSCs. The effect was regulated by miRNAs and undifferentiated MSC markers. miR-101-3p and ETV1 were the key factors and were regulated by IGF-1.

Keyphrases

mesenchymal stem cells
umbilical cord
endothelial cells
immune response
acute lymphoblastic leukemia
bone marrow
induced pluripotent stem cells
cell therapy
pluripotent stem cells
signaling pathway