Thermoneutral Housing and a Western Diet Combination Exacerbates Dysferlin-Deficient Muscular Dystrophy.
Graham S DonenZoe WhiteElodie SaugeMorten RitsoMarine TheretJohn BoydAngela M DevlinFabio M V RossiPascal BernatchezPublished in: Muscle & nerve (2022)
TN and WD combination exacerbates rodent LGMD2b without affecting WT mice. This improves rodent modeling of human MD and helps elucidate how metabolic abnormalities may play a causal role in muscle wasting.