Histological characteristics of lung adenocarcinoma with uncommon actionable alterations: special emphasis on MET exon 14 skipping alterations.

Takuo HayashiShinji KohsakaKazuya TakamochiSatsuki KishikawaDaiki IkarashiKei SanoKieko HaraHiroko OnagiYoshiyuki SueharaFumiyuki TakahashiTsuyoshi SaitoTetsuya NakatsuraShigehisa KitanoKenji SuzukiTakashi Yao

Published in: Histopathology (2021)

Our data from Japanese patients showed that lung adenocarcinoma with METex14 had unique clinicopathological characteristics: tumour cells with marked nuclear pleomorphism, hyaline globules and expression of TTF-1 in elderly women who never or lightly smoked.

Keyphrases

induced apoptosis
poor prognosis
cell cycle arrest
polycystic ovary syndrome
electronic health record
middle aged
big data
tyrosine kinase
type diabetes
oxidative stress
pregnant women
adipose tissue
skeletal muscle