NAT10-mediated ac 4 C-modified ANKZF1 promotes tumor progression and lymphangiogenesis in clear-cell renal cell carcinoma by attenuating YWHAE-driven cytoplasmic retention of YAP1.

Daojia MiaoJian ShiQingyang LvDiaoyi TanChuanyi ZhaoZhiyong XiongXiaoping Zhang

Published in: Cancer communications (London, England) (2024)

These results suggested a pro-cancer role of NAT10-mediated acetylation in ccRCC and identified the NAT10/ANKZF1/YAP1 axis as an under-reported pathway involving tumor progression and lymphangiogenesis in ccRCC.

Keyphrases

poor prognosis
papillary thyroid
squamous cell
long non coding rna
anti inflammatory
lymph node metastasis
histone deacetylase