Oligopeptide Transport in Rat Lung Alveolar Epithelial Cells is Mediated by Pept2.
Hovhannes J GukasyanTomomi UchiyamaKwang-Jin KimCarsten EhrhardtSharon K WuZea BorokEdward D CrandallVincent H L LeePublished in: Pharmaceutical research (2017)
This study confirms the absence of Pept1 from rat lung alveolar epithelium in vitro. Functional Pept2 expression in type II-like cell monolayers suggests its involvement in oligopeptide lung disposition, and offers rationale for therapeutic development of di/tripeptides, peptidomimetics employing pulmonary drug delivery.