Design and Conduct of Early Clinical Studies of Immunotherapy: Recommendations from the Task Force on Methodology for the Development of Innovative Cancer Therapies 2019 (MDICT).
Martin SmoragiewiczAlex A AdjeiEmiliano CalvoJosep TaberneroAurélien MarabelleChristophe MassardJun TangElisabeth G E de VriesJean Yves DouillardLesley Seymournull nullPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2020)
Optimization of drug development methodology is required, taking into account early, late, and lower grade intolerable toxicities, novel response patterns, as well as pharmacodynamic data.