Aurélien Marabelle (Aurelien Marabelle)

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 60

Top Topics

Advanced Cancer

Squamous Cell Carcinoma

Top Venues

Journal for immunotherapy of cancer

Clinical cancer research : an official journal of the American Association for Cancer Research

Cancer discovery

Nature communications

This page only lists publications with an associated author ORCID identifier.

Publications

Laurent Mathiot, David Combarel, Justin Cagnat, Julia Delahousse, Kaissa Ouali, Aurélien Marabelle, Yohann Loriot, Santiago Ponce, Stephane Champiat, Sophie Broutin, François-Xavier Danlos
Phase 1 first-in-human dose-escalation study of ANV419 in patients with relapsed/refractory advanced solid tumors. Journal for immunotherapy of cancer 12 (5) (2024)
Neil H Segal, Ignacio Melero Bermejo, Victor Moreno, Neeltje Steeghs, Aurélien Marabelle, Kristoffer Staal Rohrberg, Maria E Rodriguez-Ruiz, Joseph P Eder, Cathy Eng, Gulam A Manji, Daniel Waterkamp, Barbara Leutgeb, Said Bouseida, Nick Flinn, Meghna Das Thakur, Markus C Elze, Hartmut Koeppen, Candice Jamois, Meret Martin-Facklam, Christopher H Lieu, Emiliano Calvo, Luis Paz-Ares, Josep Tabernero, Guillem Argilés
CEA-CD3 bispecific antibody cibisatamab with or without atezolizumab in patients with CEA-positive solid tumours: results of two multi-institutional Phase 1 trials. Nature communications 15 (1) (2024)
Jason John Luke, Diwakar Davar, Robert H Andtbacka, Nina Bhardwaj, Joshua D Brody, Jason A Chesney, Robert Coffin, Thierry de Baere, Tanja D de Gruijl, Matthew Fury, Gregory Goldmacher, Kevin J Harrington, Howard Kaufman, Ciara M Kelly, Anuradha D Khilnani, Ke Liu, Sherene Loi, Georgina V Long, Ignacio Melero Bermejo, Mark Ross Middleton, Bart Neyns, David James Pinato, Rahul A Sheth, Stephen B Solomon, Philippe Szapary, Aurélien Marabelle
Society for Immunotherapy of Cancer (SITC) recommendations on intratumoral immunotherapy clinical trials (IICT): from premalignant to metastatic disease. Journal for immunotherapy of cancer 12 (4) (2024)
Julieta Rodriguez, Capucine Baldini, Arnauld Bayle, Arnaud Pagès, François-Xavier Danlos, Damien Vasseur, Etienne Rouleau, Ludovic Lacroix, Beatriz Alonso de Castro, Vincent Goldschmidt, Lauren Seknazi, Antoine Hollebecque, Jean Marie Michot, Stephane Champiat, Aurélien Marabelle, Kaissa Ouali, Christophe Marzac, Santiago Ponce, Jean-Baptiste Micol, Nathalie Chaput, Christophe Massard, Antoine Italiano
Impact of Clonal Hematopoiesis-Associated Mutations in Phase I Patients Treated for Solid Tumors: An Analysis of the STING Trial. JCO precision oncology 8 (2024)
François-Xavier Danlos, Claudia Grajeda-Iglesias, Sylvère Durand, Allan Sauvat, Mathilde Roumier, Delphine Cantin, Emeline Colomba, Julien Rohmer, Fanny Pommeret, Giulia Baciarello, Christophe Willekens, Marc Vasse, Frank Griscelli, Jean-Eudes Fahrner, Anne-Gaëlle Goubet, Agathe Dubuisson, Lisa Derosa, Nitharsshini Nirmalathasan, Delphine Bredel, Séverine Mouraud, Caroline Pradon, Annabelle Stoclin, Flore Rozenberg, Jérôme Duchemin, Georges Jourdi, Syrine Ellouze, Françoise Levavasseur, Laurence Albigès, Jean-Charles Soria, Fabrice Barlesi, Eric Solary, Fabrice André, Frédéric Pène, Félix Ackerman, Luc Mouthon, Laurence Zitvogel, Aurélien Marabelle, Jean-Marie Michot, Michaela Fontenay, Guido Kroemer
Correction: Metabolomic analyses of COVID-19 patients unravel stage-dependent and prognostic biomarkers. Cell death & disease 15 (2) (2024)
Neil H Segal, Ignacio Melero Bermejo, Victor Moreno, Neeltje Steeghs, Aurélien Marabelle, Kristoffer Staal Rohrberg, Maria E Rodriguez-Ruiz, Joseph P Eder, Cathy Eng, Gulam A Manji, Daniel Waterkamp, Barbara Leutgeb, Said Bouseida, Nick Flinn, Meghna Das Thakur, Markus C Elze, Hartmut Koeppen, Candice Jamois, Meret Martin-Facklam, Christopher H Lieu, Emiliano Calvo, Luis Paz-Ares, Josep Tabernero, Guillem Argilés
CEA-CD3 bispecific antibody cibisatamab with or without atezolizumab in patients with CEA-positive solid tumours: results of two multi-institutional Phase 1 trials. Nature communications 15 (1) (2024)
Jason John Luke, Diwakar Davar, Robert H Andtbacka, Nina Bhardwaj, Joshua D Brody, Jason A Chesney, Robert Coffin, Thierry de Baere, Tanja D de Gruijl, Matthew Fury, Gregory Goldmacher, Kevin J Harrington, Howard Kaufman, Ciara M Kelly, Anuradha D Khilnani, Ke Liu, Sherene Loi, Georgina V Long, Ignacio Melero Bermejo, Mark Ross Middleton, Bart Neyns, David James Pinato, Rahul A Sheth, Stephen B Solomon, Philippe Szapary, Aurélien Marabelle
Society for Immunotherapy of Cancer (SITC) recommendations on intratumoral immunotherapy clinical trials (IICT): from premalignant to metastatic disease. Journal for immunotherapy of cancer 12 (4) (2024)
Neil H Segal, Ignacio Melero Bermejo, Victor Moreno, Neeltje Steeghs, Aurélien Marabelle, Kristoffer Staal Rohrberg, Maria E Rodriguez-Ruiz, Joseph P Eder, Cathy Eng, Gulam A Manji, Daniel Waterkamp, Barbara Leutgeb, Said Bouseida, Nick Flinn, Meghna Das Thakur, Markus C Elze, Hartmut Koeppen, Candice Jamois, Meret Martin-Facklam, Christopher H Lieu, Emiliano Calvo, Luis Paz-Ares, Josep Tabernero, Guillem Argilés
CEA-CD3 bispecific antibody cibisatamab with or without atezolizumab in patients with CEA-positive solid tumours: results of two multi-institutional Phase 1 trials. Nature communications 15 (1) (2024)
Julieta Rodriguez, Capucine Baldini, Arnauld Bayle, Arnaud Pagès, François-Xavier Danlos, Damien Vasseur, Etienne Rouleau, Ludovic Lacroix, Beatriz Alonso de Castro, Vincent Goldschmidt, Lauren Seknazi, Antoine Hollebecque, Jean Marie Michot, Stephane Champiat, Aurélien Marabelle, Kaissa Ouali, Christophe Marzac, Santiago Ponce, Jean-Baptiste Micol, Nathalie Chaput, Christophe Massard, Antoine Italiano
Impact of Clonal Hematopoiesis-Associated Mutations in Phase I Patients Treated for Solid Tumors: An Analysis of the STING Trial. JCO precision oncology 8 (2024)
Neil H Segal, Ignacio Melero Bermejo, Victor Moreno, Neeltje Steeghs, Aurélien Marabelle, Kristoffer Staal Rohrberg, Maria E Rodriguez-Ruiz, Joseph P Eder, Cathy Eng, Gulam A Manji, Daniel Waterkamp, Barbara Leutgeb, Said Bouseida, Nick Flinn, Meghna Das Thakur, Markus C Elze, Hartmut Koeppen, Candice Jamois, Meret Martin-Facklam, Christopher H Lieu, Emiliano Calvo, Luis Paz-Ares, Josep Tabernero, Guillem Argilés
CEA-CD3 bispecific antibody cibisatamab with or without atezolizumab in patients with CEA-positive solid tumours: results of two multi-institutional Phase 1 trials. Nature communications 15 (1) (2024)
François-Xavier Danlos, Claudia Grajeda-Iglesias, Sylvère Durand, Allan Sauvat, Mathilde Roumier, Delphine Cantin, Emeline Colomba, Julien Rohmer, Fanny Pommeret, Giulia Baciarello, Christophe Willekens, Marc Vasse, Frank Griscelli, Jean-Eudes Fahrner, Anne-Gaëlle Goubet, Agathe Dubuisson, Lisa Derosa, Nitharsshini Nirmalathasan, Delphine Bredel, Séverine Mouraud, Caroline Pradon, Annabelle Stoclin, Flore Rozenberg, Jérôme Duchemin, Georges Jourdi, Syrine Ellouze, Françoise Levavasseur, Laurence Albigès, Jean-Charles Soria, Fabrice Barlesi, Eric Solary, Fabrice André, Frédéric Pène, Félix Ackerman, Luc Mouthon, Laurence Zitvogel, Aurélien Marabelle, Jean-Marie Michot, Michaela Fontenay, Guido Kroemer
Correction: Metabolomic analyses of COVID-19 patients unravel stage-dependent and prognostic biomarkers. Cell death & disease 15 (2) (2024)
Jason John Luke, Diwakar Davar, Robert H Andtbacka, Nina Bhardwaj, Joshua D Brody, Jason A Chesney, Robert Coffin, Thierry de Baere, Tanja D de Gruijl, Matthew Fury, Gregory Goldmacher, Kevin J Harrington, Howard Kaufman, Ciara M Kelly, Anuradha D Khilnani, Ke Liu, Sherene Loi, Georgina V Long, Ignacio Melero Bermejo, Mark Ross Middleton, Bart Neyns, David James Pinato, Rahul A Sheth, Stephen B Solomon, Philippe Szapary, Aurélien Marabelle
Society for Immunotherapy of Cancer (SITC) recommendations on intratumoral immunotherapy clinical trials (IICT): from premalignant to metastatic disease. Journal for immunotherapy of cancer 12 (4) (2024)
Laurent Mathiot, David Combarel, Justin Cagnat, Julia Delahousse, Kaissa Ouali, Aurélien Marabelle, Yohann Loriot, Santiago Ponce, Stephane Champiat, Sophie Broutin, François-Xavier Danlos
Phase 1 first-in-human dose-escalation study of ANV419 in patients with relapsed/refractory advanced solid tumors. Journal for immunotherapy of cancer 12 (5) (2024)
Neil H Segal, Ignacio Melero Bermejo, Victor Moreno, Neeltje Steeghs, Aurélien Marabelle, Kristoffer Staal Rohrberg, Maria E Rodriguez-Ruiz, Joseph P Eder, Cathy Eng, Gulam A Manji, Daniel Waterkamp, Barbara Leutgeb, Said Bouseida, Nick Flinn, Meghna Das Thakur, Markus C Elze, Hartmut Koeppen, Candice Jamois, Meret Martin-Facklam, Christopher H Lieu, Emiliano Calvo, Luis Paz-Ares, Josep Tabernero, Guillem Argilés
CEA-CD3 bispecific antibody cibisatamab with or without atezolizumab in patients with CEA-positive solid tumours: results of two multi-institutional Phase 1 trials. Nature communications 15 (1) (2024)
Jason John Luke, Diwakar Davar, Robert H Andtbacka, Nina Bhardwaj, Joshua D Brody, Jason A Chesney, Robert Coffin, Thierry de Baere, Tanja D de Gruijl, Matthew Fury, Gregory Goldmacher, Kevin J Harrington, Howard Kaufman, Ciara M Kelly, Anuradha D Khilnani, Ke Liu, Sherene Loi, Georgina V Long, Ignacio Melero Bermejo, Mark Ross Middleton, Bart Neyns, David James Pinato, Rahul A Sheth, Stephen B Solomon, Philippe Szapary, Aurélien Marabelle
Society for Immunotherapy of Cancer (SITC) recommendations on intratumoral immunotherapy clinical trials (IICT): from premalignant to metastatic disease. Journal for immunotherapy of cancer 12 (4) (2024)
Laurent Mathiot, David Combarel, Justin Cagnat, Julia Delahousse, Kaissa Ouali, Aurélien Marabelle, Yohann Loriot, Santiago Ponce, Stephane Champiat, Sophie Broutin, François-Xavier Danlos
Phase 1 first-in-human dose-escalation study of ANV419 in patients with relapsed/refractory advanced solid tumors. Journal for immunotherapy of cancer 12 (5) (2024)
Laurent Mathiot, David Combarel, Justin Cagnat, Julia Delahousse, Kaissa Ouali, Aurélien Marabelle, Yohann Loriot, Santiago Ponce, Stephane Champiat, Sophie Broutin, François-Xavier Danlos
Phase 1 first-in-human dose-escalation study of ANV419 in patients with relapsed/refractory advanced solid tumors. Journal for immunotherapy of cancer 12 (5) (2024)
Sophie Postel-Vinay, Vincent K Lam, Willeke Ros, Todd M Bauer, Aaron R Hansen, Daniel C Cho, F Stephen Hodi, Jan H M Schellens, Jennifer K Litton, Sandrine Aspeslagh, Karen A Autio, Frans L Opdam, Meredith McKean, Neeta Somaiah, Stephane Champiat, Mehmet Altan, Anna Spreafico, Osama Rahma, Elaine M Paul, Christoph M Ahlers, Helen Zhou, Herbert Struemper, Shelby A Gorman, Maura Watmuff, Kaitlin M Yablonski, Niranjan Yanamandra, Michael J Chisamore, Emmett V Schmidt, Axel Hoos, Aurélien Marabelle, Jeffrey S Weber, John V Heymach
First-in-human phase I study of the OX40 agonist GSK3174998 with or without pembrolizumab in patients with selected advanced solid tumors (ENGAGE-1). Journal for immunotherapy of cancer 11 (3) (2023)
Marine Fidelle, Conrad Rauber, Carolina Alves Costa Silva, Ai-Ling Tian, Imran Lahmar, Anne-Laure Mallard de La Varende, Liwei Zhao, Cassandra Thelemaque, Isabelle Lebhar, Meriem Messaoudene, Eugenie Pizzato, Roxanne Birebent, Maxime Descartes Mbogning Fonkou, Silvia Zoppi, Anna Reni, Cécile Dalban, Marion Leduc, Gladys Ferrere, Sylvère Durand, Pierre Ly, Aymeric Silvin, Kevin Mulder, Charles-Antoine Dutertre, Florent Ginhoux, Satoru Yonekura, Maria Paula Roberti, Maryam Tidjani Alou, Safae Terrisse, Jianzhou Chen, Oliver Kepp, Angela Schippers, Norbert Wagner, Javier Suarez-Gosalvez, Sebastian Kobold, Jean-Eudes Fahrner, Corentin Richard, Jacques Bosq, Leonardo Lordello, Giacomo Vitali, Nathalie Galleron, Benoit Quinquis, Emmanuelle Le Chatelier, Lucas Blanchard, Jean-Philippe Girard, Anne Jarry, Nadine Gervois-Segain, Emmanuelle Godefroy, Nathalie Labarrière, Ronald Koschny, Romain Daillère, Benjamin Besse, Caroline Truntzer, François Ghiringhelli, Nicolas Coatnoan, Vanessa Mhanna, David Klatzmann, Damien Drubay, Laurence Albiges, Andrew Maltez Thomas, Nicola Segata, François-Xavier Danlos, Aurélien Marabelle, Bertrand Routy, Lisa Derosa, Guido Kroemer, Laurence Zitvogel
A microbiota-modulated checkpoint directs immunosuppressive intestinal T cells into cancers. Science (New York, N.Y.) 380 (6649) (2023)
Sophie Postel-Vinay, Vincent K Lam, Willeke Ros, Todd M Bauer, Aaron R Hansen, Daniel C Cho, F Stephen Hodi, Jan H M Schellens, Jennifer K Litton, Sandrine Aspeslagh, Karen A Autio, Frans L Opdam, Meredith McKean, Neeta Somaiah, Stephane Champiat, Mehmet Altan, Anna Spreafico, Osama Rahma, Elaine M Paul, Christoph M Ahlers, Helen Zhou, Herbert Struemper, Shelby A Gorman, Maura Watmuff, Kaitlin M Yablonski, Niranjan Yanamandra, Michael J Chisamore, Emmett V Schmidt, Axel Hoos, Aurélien Marabelle, Jeffrey S Weber, John V Heymach
First-in-human phase I study of the OX40 agonist GSK3174998 with or without pembrolizumab in patients with selected advanced solid tumors (ENGAGE-1). Journal for immunotherapy of cancer 11 (3) (2023)
Stephane Champiat, Hélène Salaün, Francesca Lucibello, Jean Yves Scoazec, Benjamin Besse, Ana Ines Lalanne, Etienne Rouleau, Nolwenn Metzger, Mathilde Saint-Ghislain, Thomas Ryckewaert, Sophie Gardrat, Raymond L Barnhill, Nathalie Cassoux, Marc-Henri Stern, Olivier Lantz, Leanne De Koning, Aurélien Marabelle, Manuel J Rodrigues
Exceptional Response to Dual Colony-Stimulating Factor 1 Receptor/PD-L1 Targeting After Primary Resistance to PD-1 Inhibition in a Patient With a Metastatic Uveal Melanoma. JCO precision oncology 7 (2023)
Sophie Postel-Vinay, Vincent K Lam, Willeke Ros, Todd M Bauer, Aaron R Hansen, Daniel C Cho, F Stephen Hodi, Jan H M Schellens, Jennifer K Litton, Sandrine Aspeslagh, Karen A Autio, Frans L Opdam, Meredith McKean, Neeta Somaiah, Stephane Champiat, Mehmet Altan, Anna Spreafico, Osama Rahma, Elaine M Paul, Christoph M Ahlers, Helen Zhou, Herbert Struemper, Shelby A Gorman, Maura Watmuff, Kaitlin M Yablonski, Niranjan Yanamandra, Michael J Chisamore, Emmett V Schmidt, Axel Hoos, Aurélien Marabelle, Jeffrey S Weber, John V Heymach
First-in-human phase I study of the OX40 agonist GSK3174998 with or without pembrolizumab in patients with selected advanced solid tumors (ENGAGE-1). Journal for immunotherapy of cancer 11 (3) (2023)
Valentine Grumberg, Christos Chouaid, Anne-Françoise Gaudin, Christophe Le Tourneau, Aurélien Marabelle, Isabelle Bongiovanni-Delarozière, François-Emery Cotté, Isabelle Borget
Organizational Impact of Immunotherapies in Advanced Cancers in France. JCO global oncology 9 (2023)
Pierre Decazes, Samy Ammari, Younes Belkouchi, Léo Mottay, Littisha Lawrance, Antoine de Prévia, Hugues Talbot, Siham Farhane, Paul-Henry Cournède, Aurélien Marabelle, Florian Guisier, David Planchard, Tony Ibrahim, Caroline Robert, Fabrice Barlesi, Pierre Vera, Nathalie Lassau
Synergic prognostic value of 3D CT scan subcutaneous fat and muscle masses for immunotherapy-treated cancer. Journal for immunotherapy of cancer 11 (9) (2023)
Marie Naigeon, Matthieu Roulleaux Dugage, François-Xavier Danlos, Lisa Boselli, Jean-Mehdi Jouniaux, Caroline de Oliveira, Roberto Ferrara, Boris Duchemann, Caroline Berthot, Lou Girard, Ronan Flippot, Laurence Albiges, Siham Farhane, Patrick Saulnier, Ludovic Lacroix, Frank Griscelli, Gabriel Roman, Tyler Hulett, Aurélien Marabelle, Lydie Cassard, Benjamin Besse, Nathalie Chaput
Human virome profiling identified CMV as the major viral driver of a high accumulation of senescent CD8 + T cells in patients with advanced NSCLC. Science advances 9 (45) (2023)
Younes Belkouchi, Hugues Talbot, Nathalie Lassau, Littisha Lawrance, Siham Farhane, Rahma Feki-Mkaouar, Joya Hadchiti, Lama Dawi, Julien Vibert, Paul-Henry Cournede, Clara Cousteix, Camille Mazza, Michèle Kind, Antoine Italiano, Aurélien Marabelle, Samy Ammari, Stephane Champiat
Better than RECIST and faster than iRECIST: defining the Immunotherapy Progression Decision score to better manage progressive tumors on immunotherapy. Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
François-Xavier Danlos, Matthieu Texier, Bastien Job, Séverine Mouraud, Lydie Cassard, Capucine Baldini, Andrea Varga, Andrey A Yurchenko, Audrey Rabeau, Stephane Champiat, Diane Letourneur, Delphine Bredel, Sandrine Susini, Yuna Blum, Aurelien Parpaleix, Cedric Parlavecchio, Lambros Tselikas, Jean-Eudes Fahrner, Anne-Gaëlle Goubet, Mathieu Rouanne, Saloomeh Rafie, Alae Abbassi, Ines Kasraoui, Marie Breckler, Siham Farhane, Samy Ammari, Salim Laghouati, Anas Gazzah, Ludovic Lacroix, Benjamin Besse, Nathalie M Droin, Marc Deloger, Sophie Cotteret, Julien Adam, Laurence Zitvogel, Sergey I Nikolaev, Nathalie Chaput, Christophe Massard, Jean-Charles Soria, Carlos Alberto Gomez Roca, Gérard Zalcman, David Planchard, Aurélien Marabelle
Genomic Instability and Pro-Tumoral Inflammation are associated with Primary Resistance to Anti-PD1 + Anti-Angiogenesis in Malignant Pleural Mesothelioma. Cancer discovery (2023)
Louis Meyblum, Céline Chevaleyre, Sandrine Susini, Benoit Jego, Frederic Deschamps, Dimitri Kereselidze, Baptiste Bonnet, Aurélien Marabelle, Thierry de Baere, Vincent Lebon, Lambros Tselikas, Charles Truillet
Local and distant response to intratumoral immunotherapy assessed by immunoPET in mice. Journal for immunotherapy of cancer 11 (11) (2023)
Delphine Bredel, Edi Tihic, Séverine Mouraud, François-Xavier Danlos, Sandrine Susini, Marine Aglave, Alexia Alfaro, Chifaou Mohamed-Djalim, Mathieu Rouanne, Héloise Halse, Amélie Bigorgne, Lambros Tselikas, Stéphane Dalle, Dana M Hartl, Eric Baudin, Catherine Guettier, Eric Vibert, Olivier Rosmorduc, Caroline Robert, Sophie Ferlicot, Bastien Parier, Laurence Albiges, Vincent Thomas de Montpreville, Benjamin Besse, Olaf Mercier, Caroline Even, Ingrid Breuskin, Marion Classe, Camélia Radulescu, Thierry Lebret, Patricia Pautier, Sébastien Gouy, Jean-Yves Scoazec, Laurence Zitvogel, Aurélien Marabelle, Mélodie Bonvalet
Immune checkpoints are predominantly co-expressed by clonally expanded CD4 + FoxP3 + intratumoral T-cells in primary human cancers. Journal of experimental & clinical cancer research : CR 42 (1) (2023)
Emily Alouani, Benoit Rousseau, Thierry André, Aurélien Marabelle
Immunotherapy advances in cancers with mismatch repair or proofreading deficiencies. Nature cancer 3 (12) (2022)
David M O'Malley, Giovanni Mendonca Bariani, Philippe Alexandre Cassier, Aurélien Marabelle, Aaron Richard Hansen, Ana De Jesus Acosta, Wilson H Miller, Tamar Safra, Antoine Italiano, Linda Mileshkin, Lei Xu, Fan Jin, Kevin Norwood, Michele Maio
Pembrolizumab in Patients With Microsatellite Instability-High Advanced Endometrial Cancer: Results From the KEYNOTE-158 Study. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 40 (7) (2022)
Benoit Rousseau, Ivan Bièche, Éric Pasmant, Nadim Hamzaoui, Nicolas Leulliot, Lucas Michon, Aurélien de Reyniès, Valerie Attignon, Michael B Foote, Julien Masliah-Planchon, Magali Svrcek, Romain Cohen, Victor Simmet, Paule Augereau, David Malka, Antoine Hollebecque, Damien Pouessel, Carlos Alberto Gomez Roca, Rosine Guimbaud, Amandine Bruyas, Marielle Guillet, Jean-Jacques Grob, Muriel Duluc, Sophie Cousin, Christelle De La Fouchardière, Aude Flechon, Frédéric Rolland, Sandrine Hiret, Esma Saada-Bouzid, Olivier Bouche, Thierry André, Diane Pannier, Farid El Hajbi, Stephane Marie Oudard, Christophe Tournigand, Jean-Charles Soria, Stephane Champiat, Drew G Gerber, Dennis Stephens, Michelle F Lamendola-Essel, Steven B Maron, Bill H Diplas, Guillem Argilés, Asha R Krishnan, Séverine Tabone-Eglinger, Anthony Ferrari, Neil H Segal, Andrea Cercek, Natalie Hoog-Labouret, Frederic Legrand, Clotilde Simon, Assia Lamrani-Ghaouti, Luis A Diaz, Pierre Saintigny, Sylvie Chevret, Aurélien Marabelle
PD-1 Blockade in Solid Tumors with Defects in Polymerase Epsilon. Cancer discovery 12 (6) (2022)
Mihaela Aldea, Fabrice Andre, Aurélien Marabelle, Semih Dogan, Fabrice Barlesi, Jean-Charles Soria
Overcoming Resistance to Tumor-Targeted and Immune-Targeted Therapies. Cancer discovery 11 (4) (2022)
Emily Alouani, Benoit Rousseau, Thierry André, Aurélien Marabelle
Immunotherapy advances in cancers with mismatch repair or proofreading deficiencies. Nature cancer 3 (12) (2022)
Jean-Eudes Fahrner, Imran Lahmar, Anne-Gaëlle Goubet, Yacine Haddad, Agathe Carrier, Marine Mazzenga, Damien Drubay, Carolina Alves Costa Silva, null null, Eric de Sousa, Cassandra Thelemaque, Cléa Melenotte, Agathe Dubuisson, Arthur Geraud, Gladys Ferrere, Roxanne Birebent, Camille Bigenwald, Marion Picard, Luigi Cerbone, Joana R Lérias, Ariane Laparra, Alice Bernard-Tessier, Benoît Kloeckner, Marianne Gazzano, François-Xavier Danlos, Safae Terrisse, Eugenie Pizzato, Caroline Flament, Pierre Ly, Eric Tartour, Nadine Benhamouda, Lydia Meziani, Abdelhakim Ahmed-Belkacem, Makoto Miyara, Guy Gorochov, Fabrice Barlesi, Alexandre Trubert, Benjamin Ungar, Yeriel Estrada, Caroline Pradon, Emmanuelle Gallois, Fanny Pommeret, Emeline Colomba, Pernelle Lavaud, Marc Deloger, Nathalie M Droin, Eric Deutsch, Bertrand Gachot, Jean-Philippe Spano, Mansouria Merad, Florian Scotté, Aurélien Marabelle, Frank Griscelli, Jean Yves Blay, Jean-Charles Soria, Miriam Merad, Fabrice Andre, Juliette Villemonteix, Mathieu F Chevalier, Sophie Caillat-Zucman, Florence Fenollar, Emma Guttman-Yassky, Odile Launay, Guido Kroemer, Bernard La Scola, Markus Maeurer, Lisa Derosa, Laurence Zitvogel
The Polarity and Specificity of Antiviral T Lymphocyte Responses Determine Susceptibility to SARS-CoV-2 Infection in Patients with Cancer and Healthy Individuals. Cancer discovery 12 (4) (2022)
Jonathan Wade Goldman, Sarina A Piha-Paul, Brendan D Curti, Katrina S Pedersen, Todd M Bauer, Stefanie L Groenland, Richard D Carvajal, Vaishali Chhaya, Gray Kirby, Kelly McGlinchey, Scott A Hammond, Katie Streicher, Danielle M Townsley, Young Kwang Chae, Jens Voortman, Aurélien Marabelle, John D Powderly
Safety and Tolerability of MEDI0562, an OX40 Agonist mAb, in Combination with Durvalumab or Tremelimumab in Adult Patients with Advanced Solid Tumors. Clinical cancer research : an official journal of the American Association for Cancer Research 28 (17) (2022)
Anne-Gaëlle Goubet, Leonardo Lordello, Carolina Alves Costa Silva, Isabelle Peguillet, Marianne Gazzano, Maxime Descartes Mbogning Fonkou, Cassandra Thelemaque, Cedric Lebacle, Constance Thibault, Francois Audenet, Géraldine Pignot, Gwenaëlle Gravis, Carole Helissey, Luca Campedel, Morgan Roupret, Evanguelos Xylinas, Idir Ouzaid, Agathe Dubuisson, Marine Mazzenga, Caroline Flament, Pierre Ly, Virginie Marty, Nicolas Signolle, Allan Sauvat, Thomas Sbarrato, Mounia Filahi, Caroline Davin, Gabriel Haddad, Jacques Yb Khalil, Camille Blériot, François-Xavier Danlos, Garett Dunsmore, Kevin Mulder, Aymeric Silvin, Thibault Raoult, Baptiste Archambaud, Shaima Belhechmi, Ivo Gomperts Boneca, Nadège Cayet, Maryse Moya-Nilges, Adeline Mallet, Romain Daillère, Etienne Rouleau, Camelia Radulescu, Yves Allory, Jacques Fieschi, Mathieu Rouanne, Florent Ginhoux, Gwénaël Le Teuff, Lisa Derosa, Aurélien Marabelle, Jeroen van Dorp, Nick van Dijk, Michiel S Van Der Heijden, Benjamin Besse, Fabrice Andre, Miriam Merad, Guido Kroemer, Jean Yves Scoazec, Laurence Zitvogel, Yohann Loriot
Escherichia coli-Specific CXCL13-Producing TFH Are Associated with Clinical Efficacy of Neoadjuvant PD-1 Blockade against Muscle-Invasive Bladder Cancer. Cancer discovery 12 (10) (2022)
Emily Alouani, Benoit Rousseau, Thierry André, Aurélien Marabelle
Immunotherapy advances in cancers with mismatch repair or proofreading deficiencies. Nature cancer 3 (12) (2022)
Boris Duchemann, Marie Naigeon, Edouard Auclin, Roberto Ferrara, Lydie Cassard, Jean-Mehdi Jouniaux, Lisa Boselli, Jonathan Grivel, Aude Desnoyer, François-Xavier Danlos, Laura Mezquita, Caroline Caramella, Aurélien Marabelle, Benjamin Besse, Nathalie Chaput
CD8 + PD-1 + to CD4 + PD-1 + ratio (PERLS) is associated with prognosis of patients with advanced NSCLC treated with PD-(L)1 blockers. Journal for immunotherapy of cancer 10 (2) (2022)
Laetitia Nebot-Bral, Antoine Hollebecque, Andrey A Yurchenko, Louise de Forceville, Mathieu Danjou, Jean-Mehdi Jouniaux, Reginaldo C A Rosa, Caroline Pouvelle, Said Aoufouchi, Perrine Vuagnat, Cristina Smolenschi, Emeline Colomba, Alexandra Leary, Aurélien Marabelle, Jean-Yves Scoazec, Lydie Cassard, Sergey Nikolaev, Nathalie Chaput, Patricia L Kannouche
Overcoming resistance to αPD-1 of MMR-deficient tumors with high tumor-induced neutrophils levels by combination of αCTLA-4 and αPD-1 blockers. Journal for immunotherapy of cancer 10 (7) (2022)
Carlos Gomez-Roca, Philippe Cassier, Dmitriy Zamarin, Jean-Pascal H Machiels, Jose Luis Perez Gracia, F Stephen Hodi, Alvaro Taus, Maria Martinez Garcia, Valentina Boni, Joseph P Eder, Navid Hafez, Ryan J Sullivan, David Mcdermott, Stephane Champiat, Sandrine Aspeslagh, Catherine Terret, Anna-Maria Jegg, Wolfgang Jacob, Michael A Cannarile, Carola Ries, Konstanty Korski, Francesca Michielin, Randolph Christen, Galina Babitzki, Carl Watson, Georgina Meneses-Lorente, Martin Weisser, Dominik Rüttinger, Jean-Pierre Delord, Aurélien Marabelle
Anti-CSF-1R emactuzumab in combination with anti-PD-L1 atezolizumab in advanced solid tumor patients naïve or experienced for immune checkpoint blockade. Journal for immunotherapy of cancer 10 (5) (2022)
Laurent Dercle, Jeremy McGale, Shawn Sun, Aurélien Marabelle, Randy Yeh, Eric Deutsch, Fatima-Zohra Mokrane, Michael Farwell, Samy Ammari, Heiko Schoder, Binsheng Zhao, Lawrence H Schwartz
Artificial intelligence and radiomics: fundamentals, applications, and challenges in immunotherapy. Journal for immunotherapy of cancer 10 (9) (2022)
Ana Costa, Cécile Thirant, Amira Kramdi, Cécile Pierre-Eugène, Caroline Louis-Brennetot, Orphée Blanchard, Didier Surdez, Nadege Gruel, Eve Lapouble, Gaëlle Pierron, Deborah Sitbon, Hervé Brisse, Arnaud Gauthier, Paul Fréneaux, Mylène Bohec, Virginie Raynal, Sylvain Baulande, Renaud Leclere, Gabriel Champenois, Andre Nicolas, Didier Meseure, Angela Bellini, Aurélien Marabelle, Birgit Geoerger, Fatima Mechta-Grigoriou, Gudrun Schleiermacher, Laurie Menger, Olivier Delattre, Isabelle Janoueix-Lerosey
Single-cell transcriptomics reveals shared immunosuppressive landscapes of mouse and human neuroblastoma. Journal for immunotherapy of cancer 10 (8) (2022)
Lillian Siu, Joshua Brody, Shilpa Gupta, Aurélien Marabelle, Antonio Jimeno, Pamela Munster, Juneko Grilley-Olson, Alain H Rook, Antoine Hollebecque, Rebecca K S Wong, James W Welsh, Yuling Wu, Christopher Morehouse, Oday Hamid, Farzana Walcott, Zachary A Cooper, Rakesh Kumar, Charles Ferté, David S Hong
Safety and clinical activity of intratumoral MEDI9197 alone and in combination with durvalumab and/or palliative radiation therapy in patients with advanced solid tumors. Journal for immunotherapy of cancer 8 (2) (2021)
Mathieu Rouanne, Laurence Zitvogel, Aurélien Marabelle
Pegylated Engineered IL2 plus Anti-PD-1 Monoclonal Antibody: The Nectar Comes from the Combination. Cancer discovery 10 (8) (2021)
François-Xavier Danlos, Claudia Grajeda-Iglesias, Sylvère Durand, Allan Sauvat, Mathilde Roumier, Delphine Cantin, Emeline Colomba, Julien Rohmer, Fanny Pommeret, Giulia Baciarello, Christophe Willekens, Marc Vasse, Frank Griscelli, Jean-Eudes Fahrner, Anne-Gaëlle Goubet, Agathe Dubuisson, Lisa Derosa, Nitharsshini Nirmalathasan, Delphine Bredel, Séverine Mouraud, Caroline Pradon, Annabelle Stoclin, Flore Rozenberg, Jérôme Duchemin, Georges Jourdi, Syrine Ellouze, Françoise Levavasseur, Laurence Albigès, Jean-Charles Soria, Fabrice Barlesi, Eric Solary, Fabrice André, Frédéric Pène, Félix Ackerman, Luc Mouthon, Laurence Zitvogel, Aurélien Marabelle, Jean-Marie Michot, Michaela Fontenay, Guido Kroemer
Metabolomic analyses of COVID-19 patients unravel stage-dependent and prognostic biomarkers. Cell death & disease 12 (3) (2021)
Aude De Gassart, Kieu-Suong Le, Patrick Brune, Sophie Agaugué, Jennifer Sims, Armelle Goubard, Rémy Castellano, Noémie Joalland, Emmanuel Scotet, Yves Collette, Emmanuel Valentin, Clement Ghigo, Christine Pasero, Magali Colazet, Jaime Guillén, Carla E Cano, Aurélien Marabelle, Johann S de Bono, René Hoet, Alemseged Truneh, Daniel Olive, Paul A Frohna
Development of ICT01, a first-in-class, anti-BTN3A antibody for activating Vγ9Vδ2 T cell-mediated antitumor immune response. Science translational medicine 13 (616) (2021)
Lambros Tselikas, Thierry de Baere, Thomas Isoardo, Sandrine Susini, Karine Ser-Le Roux, Mélanie Polrot, Julien Adam, Mathieu Rouanne, Laurence Zitvogel, Laurence Moine, Fréderic Deschamps, Aurélien Marabelle
Pickering emulsions with ethiodized oil and nanoparticles for slow release of intratumoral anti-CTLA4 immune checkpoint antibodies. Journal for immunotherapy of cancer 8 (1) (2021)
Filippo G Dall'Olio, Aurélien Marabelle, Caroline Caramella, Camilo Garcia, Mihaela Aldea, Nathalie Chaput, Caroline Robert, Benjamin Besse
Tumour burden and efficacy of immune-checkpoint inhibitors. Nature reviews. Clinical oncology (2021)
Ignacio Melero Bermejo, Eduardo Castanon, Maite Alvarez, Stephane Champiat, Aurélien Marabelle
Intratumoural administration and tumour tissue targeting of cancer immunotherapies. Nature reviews. Clinical oncology 18 (9) (2021)
Lambros Tselikas, Stephane Champiat, Rahul A Sheth, Steve Yevich, Samy Ammari, Frederic Deschamps, Siham Farhane, Charles Roux, Sandrine Susini, Séverine Mouraud, Alexandre Delpla, Thibault Raoult, Caroline Robert, Christophe Massard, Fabrice Barlesi, Jean-Charles Soria, Aurélien Marabelle, Thierry de Baere
Interventional Radiology for Local Immunotherapy in Oncology. Clinical cancer research : an official journal of the American Association for Cancer Research 27 (10) (2021)
James F Spicer, Aurélien Marabelle, Jean-Francois Baurain, Nina Louise Jebsen, Dag Erik Jøssang, Ahmad Awada, Rebecca S Kristeleit, Delphine Loirat, George Lazaridis, Christiane Jungels, Paal Brunsvig, Berit Nicolaisen, Andrew Saunders, Hamina Patel, Jerome Galon, Fabienne Hermitte, Ketil André Camilio, Brynjar Mauseth, Vibeke Sundvold, Baldur Sveinbjørnsson, Øystein Rekdal
Safety, Antitumor Activity, and T-cell Responses in a Dose-Ranging Phase I Trial of the Oncolytic Peptide LTX-315 in Patients with Solid Tumors. Clinical cancer research : an official journal of the American Association for Cancer Research 27 (10) (2021)
David S Hong, Aparna Parikh, Geoffrey I Shapiro, Andrea Varga, Aung Naing, Funda Meric-Bernstam, Özlem Ataman, Larisa Reyderman, Terri A Binder, Min Ren, Mingjie Liu, Satish Dayal, Amy Y Siu, Pallavi Sachdev, Lucy Xu, Vijay Bhagawati-Prasad, Ilian Tchakov, Chean Eng Ooi, Xingfeng Bao, Aurélien Marabelle
First-in-human phase I study of immunomodulatory E7046, an antagonist of PGE2-receptor E-type 4 (EP4), in patients with advanced cancers. Journal for immunotherapy of cancer 8 (1) (2021)
Anne-Gaëlle Goubet, Agathe Dubuisson, Arthur Geraud, François-Xavier Danlos, Safae Terrisse, Carolina Alves Costa Silva, Damien Drubay, Lea Touri, Marion Picard, Marine Mazzenga, Aymeric Silvin, Garett Dunsmore, Yacine Haddad, Eugenie Pizzato, Pierre Ly, Caroline Flament, Cléa Melenotte, Eric Solary, Michaela Fontenay, Gabriel Garcia, Corinne Balleyguier, Nathalie Lassau, Markus Maeurer, Claudia Grajeda-Iglesias, Nitharsshini Nirmalathasan, Fanny Aprahamian, Sylvère Durand, Oliver Kepp, Gladys Ferrere, Cassandra Thelemaque, Imran Lahmar, Jean-Eudes Fahrner, Lydia Meziani, Abdelhakim Ahmed-Belkacem, Nadia Saïdani, Bernard La Scola, Didier Raoult, Stéphanie Gentile, Sébastien Cortaredona, Giuseppe Ippolito, Benjamin Lelouvier, Alain Roulet, Fabrice Andre, Fabrice Barlesi, Jean-Charles Soria, Caroline Pradon, Emmanuelle Gallois, Fanny Pommeret, Emeline Colomba, Florent Ginhoux, Suzanne Kazandjian, Arielle Elkrief, Bertrand Routy, Makoto Miyara, Guy Gorochov, Eric Deutsch, Laurence Albiges, Annabelle Stoclin, Bertrand Gachot, Anne Florin, Mansouria Merad, Florian Scotte, Souad Assaad, Guido Kroemer, Jean Yves Blay, Aurélien Marabelle, Frank Griscelli, Laurence Zitvogel, Lisa Derosa
Prolonged SARS-CoV-2 RNA virus shedding and lymphopenia are hallmarks of COVID-19 in cancer patients with poor prognosis. Cell death and differentiation 28 (12) (2021)
Tala Shekarian, Eva Sivado, Anne-Catherine Jallas, Stéphane Depil, Janice Kielbassa, Isabelle Janoueix-Lerosey, Gregor Hutter, Nadège Goutagny, Christophe Bergeron, Alain Viari, Sandrine Valsesia-Wittmann, Christophe Caux, Aurélien Marabelle
Repurposing rotavirus vaccines for intratumoral immunotherapy can overcome resistance to immune checkpoint blockade. Science translational medicine 11 (515) (2020)
Martin Smoragiewicz, Alex A Adjei, Emiliano Calvo, Josep Tabernero, Aurélien Marabelle, Christophe Massard, Jun Tang, Elisabeth G E de Vries, Jean Yves Douillard, Lesley Seymour, null null
Design and Conduct of Early Clinical Studies of Immunotherapy: Recommendations from the Task Force on Methodology for the Development of Innovative Cancer Therapies 2019 (MDICT). Clinical cancer research : an official journal of the American Association for Cancer Research 26 (11) (2020)
Roberto Ferrara, Marie Naigeon, Edouard Auclin, Boris Duchemann, Lydie Cassard, Jean-Mehdi Jouniaux, Lisa Boselli, Jonathan Grivel, Aude Desnoyer, Laura Mezquita, Matthieu Texier, Caroline Caramella, Lizza E L Hendriks, David Planchard, Jordi Remon, Sabina Sangaletti, Claudia Proto, Marina C Garassino, Jean-Charles Soria, Aurélien Marabelle, Anne-Laure Voisin, Siham Farhane, Benjamin Besse, Nathalie Chaput
Circulating T-cell Immunosenescence in Patients with Advanced Non-small Cell Lung Cancer Treated with Single-agent PD-1/PD-L1 Inhibitors or Platinum-based Chemotherapy. Clinical cancer research : an official journal of the American Association for Cancer Research 27 (2) (2020)
Stephane Champiat, Lambros Tselikas, Siham Farhane, Thibault Raoult, Matthieu Texier, Emilie Lanoy, Christophe Massard, Caroline Robert, Samy Ammari, Thierry De Baère, Aurélien Marabelle
Intratumoral Immunotherapy: From Trial Design to Clinical Practice. Clinical cancer research : an official journal of the American Association for Cancer Research 27 (3) (2020)
Caroline Robert, Aurélien Marabelle, Hugo Herrscher, Caroline Caramella, Pascal Rouby, Karim Fizazi, Benjamin Besse
Immunotherapy discontinuation - how, and when? Data from melanoma as a paradigm. Nature reviews. Clinical oncology 17 (11) (2020)
Mark Aleynick, Judit Svensson-Arvelund, Christopher R Flowers, Aurélien Marabelle, Joshua D Brody
Pathogen Molecular Pattern Receptor Agonists: Treating Cancer by Mimicking Infection. Clinical cancer research : an official journal of the American Association for Cancer Research 25 (21) (2019)