IL10 promoter rs6667202 polymorphism is functional in health but not in grade c periodontitis patients: A pilot study.
Camila S StolfCatharina M SacramentoHélvis E S PazRenato A MachadoLucas P RamosLuciane D de OliveiraKarina Cogo-MüllerMauro Pedrine SantamariaKarina Gonzalez Silvério RuizRenato Correa Viana CasarinPublished in: Journal of periodontal research (2021)
The rs6667202 SNP is functional in PH, as it decreases the expression and production of IL-10. In Perio4C, other factors may be masking its action by altering the IL-10's response.