Continuous measurement of breast tumour hormone receptor expression: a comparison of two computational pathology platforms.

Thomas Patrick AhernAndrew H BeckBernard A RosnerBen GlassGretchen FrielingLaura C CollinsRulla M Tamimi

Published in: Journal of clinical pathology (2016)

Paired hormone receptor expression measurements from two different computational pathology platforms agreed well with one another. The user-supervised workflow yielded better classification accuracy than the automated workflow. Appropriately validated computational pathology algorithms enrich molecular epidemiology studies with continuous protein expression data and may accelerate tumour biomarker discovery.

Keyphrases

machine learning
poor prognosis
deep learning
electronic health record
big data
high throughput
artificial intelligence
data analysis