The effect of filum terminale sectioning for Chiari 1 malformation treatment: systematic review.

Jerônimo Buzetti MilanoAlécio Cristino Evangelista Santos BarcelosFranz Jooji OnishiJefferson Walter DanielRicardo Vieira BotelhoFernando Rolemberg DantasEloy Rusafa NetoEduardo de Freitas BertoliniMarcelo Luís MudoRoger S BrockRicardo Santos de OliveiraAndrei Fernandes Joaquim

Published in: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology (2019)

There is no scientific support for filum terminale sectioning in patients with CM without evidence of tethered cord. This procedure may be considered experimental and should be validated in a strict criterion of inclusion clinical trial comparing outcomes in posterior fossa decompression.

Keyphrases

systematic review
clinical trial
minimally invasive
meta analyses
open label
randomized controlled trial
phase ii
metabolic syndrome
type diabetes
double blind
combination therapy
replacement therapy
smoking cessation
glycemic control