Anti-cancer effects of Bifidobacterium species in colon cancer cells and a mouse model of carcinogenesis.

Parisa AsadollahiRoya GhanavatiMahdi RohaniShabnam RazaviMaryam EsghaeiMalihe Talebi

Published in: PloS one (2020)

BC was the most efficient treatment in this study. It had considerable "protective" anti-cancer properties and concomitantly down regulated EGFR, HER-2 and PTGS-2 (COX-2), while having significant anti-CRC effects on CRC mice models. In general, this potential probiotic could be considered as a suitable nutritional supplement to treat and prevent CRC.

Keyphrases

mouse model
small cell lung cancer
epidermal growth factor receptor
transcription factor
tyrosine kinase
high fat diet induced
adipose tissue
insulin resistance
bacillus subtilis
lactic acid