B-cell phenotype and IgD-CD27- memory B cells are affected by TNF-inhibitors and tocilizumab treatment in rheumatoid arthritis.

Rita A MouraCláudia QuaresmaAna R VieiraMaria J GonçalvesJoaquim Polido-PereiraVasco C RomãoNádia MartinsHelena CanhãoJoão E Fonseca

Published in: PloS one (2017)

In RA patients, the use of TNF-inhibitors and/ or tocilizumab treatment affects B-cell phenotype and IgD-CD27- memory B cells in circulation, but not B-cell gene expression levels.

Keyphrases

rheumatoid arthritis
gene expression
disease activity
end stage renal disease
ankylosing spondylitis
newly diagnosed
ejection fraction
interstitial lung disease
chronic kidney disease
rheumatoid arthritis patients
systemic lupus erythematosus
systemic sclerosis
patient reported