Sperm Mitochondrial Content and Mitochondrial DNA to Nuclear DNA Ratio Are Associated with Body Mass Index and Progressive Motility.
Efthalia MoustakliAthanasios ZikopoulosCharikleia SkentouIoanna BoubaGeorgia TsirkaSofoklis StavrosDionysios VrachnisNikolaos DrakoulisAnastasios PotirisIoannis GeorgiouAthanasios ZachariouPublished in: Biomedicines (2023)
We found that in all three groups, BMI and progressive motility exhibited comparable relationships with mitochondrial DNA expression and the mtDNA/nDNA ratio. However, only in the normal group and in the obese group, the relative mitochondrial DNA copy number showed a positive association with BMI and progressive motility.
Keyphrases
- mitochondrial dna
- copy number
- multiple sclerosis
- biofilm formation
- body mass index
- genome wide
- poor prognosis
- dna methylation
- adipose tissue
- oxidative stress
- metabolic syndrome
- weight gain
- pseudomonas aeruginosa
- type diabetes
- single molecule
- escherichia coli
- staphylococcus aureus
- circulating tumor
- candida albicans
- cell free
- gene expression
- binding protein
- bariatric surgery
- obese patients
- circulating tumor cells