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The effect of years of schooling and age on CERAD-MX performance in Mexican preclinical carriers of the APP V717I mutation: Randomized data simulation.

Angélica Zuno-ReyesKarina Pérez-RubioMartín Alonso Flores-GonzálezRicardo Jauregui TorresSofía Dumois-PetersenLuis E FigueraJohn M RingmanEsmeralda Matute
Published in: Alzheimer's & dementia (Amsterdam, Netherlands) (2024)
preclinical carriers.Preclinical carriers underperformed non-carriers on Constructional Praxis Recall.Fewer YoS emerges as a confounding variable when detecting cognitive failures.Younger participants in both groups overperformed the older ones in the Memory tasks.Randomized data simulation increases statistical power when analyzing rare diseases.
Keyphrases
  • double blind
  • open label
  • placebo controlled
  • cell therapy
  • electronic health record
  • phase iii
  • working memory
  • big data
  • clinical trial
  • randomized controlled trial
  • stem cells
  • data analysis
  • study protocol