Open-label long-term treatment of add-on triheptanoin in adults with drug-resistant epilepsy.
Karin BorgesNeha KaulJack GermaineCatalina Carrasco-PozoPatrick KwanTerence J O'BrienPublished in: Epilepsia open (2020)
Our results indicate antiseizure effects of triheptanoin on focal seizures in 5 out of 10 adults. However, only two people finished and extended the 48-week add-on treatment phase, despite lack of safety or tolerability issues.More studies focused on improved treatment formulations, the potential of lower dosages, and efficacy are needed. Trial registration number: ACTRN12615000406505.