Assessing the external validity of the VALIDATE-SWEDEHEART trial.

Rebecca Tremain RylancePhilippe WagnerElmir OmerovicClaes HeldStefan JamesSasha KoulDavid Erlinge

Published in: Clinical trials (London, England) (2021)

The propensity score difference demonstrated that the screened not-enrolled with fulfilled inclusion criteria and trial population were not similar. The inverse-probability weighted analysis showed no significant differences in mortality. From this, we conclude that the VALIDATE results may be generalized to the screened not-enrolled with fulfilled inclusion criteria.

Keyphrases

phase iii
study protocol
phase ii
clinical trial
magnetic resonance
cardiovascular events
randomized controlled trial
open label
contrast enhanced
computed tomography
network analysis