Angiopoietin-2 associates with poor prognosis in Moyamoya angiopathy.
Gemma GorlaAntonella PotenzaTatiana CarrozziniGiuliana PollaciFrancesco AcerbiIgnazio G VetranoPaolo FerroliIsabella CanaveroNicola RifinoAnna BersanoLaura GattiPublished in: Annals of clinical and translational neurology (2024)
Our results pointed out Ang-2 as a reliable biomarker mirroring arterial steno-occlusion and vascular instability of MA in CSF and blood, providing a candidate factor for patient stratification. This pilot study may pave the way to the validation of a biomarker to identify progressive MA patients deserving a specific treatment path.