The miR-204-5p/FOXC1/GDF7 axis regulates the osteogenic differentiation of human adipose-derived stem cells via the AKT and p38 signalling pathways.

You ZhouSiyu LiuWei WangQiang SunMengzhu LvShude YangShuang TongShu Guo

Published in: Stem cell research & therapy (2021)

Our results demonstrated that the miR-204-5p/FOXC1/GDF7 axis regulates the osteogenic differentiation of hADSCs via the AKT and p38 signalling pathways. This study further revealed the regulatory mechanism of hADSC differentiation from the perspective of miRNA regulation.

Keyphrases

signaling pathway
cell proliferation
endothelial cells
transcription factor
single cell
pluripotent stem cells