Knockdown of Circular RNA Hsa_circ_0000714 Can Regulate RAB17 by Sponging miR-370-3p to Reduce Paclitaxel Resistance of Ovarian Cancer Through CDK6/RB Pathway.

Min GuoShuo LiXiaoyun ZhaoYing YuanBin ZhangYifu Guan

Published in: OncoTargets and therapy (2020)

Hsa_circ_0000714 acts as a sponge for miR-370-3p, and regulates RAB17 expression through the CDK6/RB signaling pathway, which plays a role in the malignant progression of the paclitaxel-resistant ovarian cancer cell A2780/PTX.

Keyphrases

cell cycle
signaling pathway
poor prognosis
pi k akt
epithelial mesenchymal transition
chemotherapy induced
binding protein
induced apoptosis